| Full text | |
| Author(s): |
Alexandrino, Guilherme L.
[1]
;
de Sousa Junior, Gustavo R.
[1]
;
Reis, Francisco de A. M.
[1]
;
Augusto, Fabio
[1]
Total Authors: 4
|
| Affiliation: | [1] Univ Estadual Campinas, Inst Chem, Cidade Univ Zeferino Vaz, BR-13083970 Campinas, SP - Brazil
Total Affiliations: 1
|
| Document type: | Journal article |
| Source: | Journal of Chromatography A; v. 1536, p. 82-87, FEB 9 2018. |
| Web of Science Citations: | 5 |
| Abstract | |
The enhanced chromatographic capability of the comprehensive two-dimensional gas chromatography (GC x GC) has already found several applications in analytical chemistry comprising complex samples. However, setting the appropriate chromatographic conditions that maximize sensitivity and separation efficiency in GC x GC may be more difficult than in conventional one-dimension gas chromatography, mainly due to the additional parameters strictly related to the modulation. Loop-type cryogenic modulators have been currently used for crude oil analysis using GC x GC, requiring sometimes a laborious try-and-error procedure to properly tune the dual jets elapsed times on modulation. In this work, the advantages of choosing a time-variable combination of cold and hot jets pulses in a loop-type cryogenic modulator is presented when performing the fingerprinting analysis of crude oils using GC x GC-QMS, contrary to the conventional procedure based on a single combination for the dual-stage jets. A design of experiments approach is proposed to most effectively optimize the time-variable combination of the dual-jets elapsed times while modulating the wide hydrocarbons range along the GC x GC analysis. The most abundant classes of hydrocarbons contained in the maltenes fraction of a crude oil sample, such as paraffins, aromatics, steranes and hopanes were successfully resolved. (C) 2017 Elsevier B.V. All rights reserved. (AU) | |
| FAPESP's process: | 15/08201-0 - Petroleomics: an approach using comprehensive Two-Dimension gas chromatography coupled with mass spectrometry and chemometrics |
| Grantee: | Guilherme Lionello Alexandrino |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |