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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

High blood lead levels are associated with lead concentrations in households and day care centers attended by Brazilian preschool children

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Autor(es):
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da Rocha Silva, Julia Prestes [1] ; Salles, Fernanda Junqueira [1] ; Leroux, Isabelle Nogueira [1] ; Sacone da Silva Ferreira, Ana Paula [1] ; da Silva, Agnes Soares [2] ; Assuncao, Nilson Antonio [3] ; Nardocci, Adelaide Cassia [1] ; Sayuri Sato, Ana Paula [4] ; Barbosa, Jr., Fernando [5] ; Alves Cardoso, Maria Regina [4] ; Kaneshiro Olympio, Kelly Polido [1]
Número total de Autores: 11
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Fac Saude Pabl, Dept Saude Ambiental, Av Dr Arnaldo 715, Cerqueira Cesar, BR-01246904 Sao Paulo, SP - Brazil
[2] Pan Amer Hlth Org, Sustainable Dev & Hlth Equ, Washington, DC - USA
[3] Univ Fed Sao Paulo, Inst Ciencias Ambientais Quim & Farmaceut, Dept Quim, Diadema, SP - Brazil
[4] Univ Sao Paulo, Fac Saude Publ, Dept Epidemiol, Sao Paulo, SP - Brazil
[5] Univ Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, Dept Anal Clin Toxicol & Bromatol, Sao Paulo, SP - Brazil
Número total de Afiliações: 5
Tipo de documento: Artigo Científico
Fonte: Environmental Pollution; v. 239, p. 681-688, AUG 2018.
Citações Web of Science: 4
Resumo

Background: A previous study observed high blood lead levels (BLL) in preschool children attending 50 day care centers (DCC) in sao Paulo, Brazil. Objective: To identify whether lead levels found in both homes and DCC environments are associated with high blood lead levels. Methods: Children attending 4 DCCs, quoted here as NR, VA, PS and PF, were divided into two groups according to BLL: high exposure (HE: >= 13.9 mu g/dL; 97.5 percentile of the 2013 year sample) and low exposure (LE: <5 mu g/dL). For in situ lead measurements (lead paint mode: mg/cm(2) and ROHS mode: mu g/g) in the children's households and in the DCC environments, a field portable X-ray-fluorescence analyzer was used. Multiple logistic regressions were performed to control for confounding factors. Odds ratios were adjusted for age, sex, day care center's measured lead, and tobacco. Results: In an NR DCC building, 33.8% of the measurements had lead levels >600 mu g/g, whereas such levels were observed in 77.1% of NR playground measurements. In VA DCC, 22% and 23% of the measurements in the building and in the playgrounds had levels higher than 600 mu g/g, respectively. The percentage of high lead levels in the children's houses of the LE group was 5.9% (95% CI: 4.3-7.6%) and 13.2 (95% CI: 8.3-18.0%) in the HE group. Moreover, a significant association was found between high BLLs and lead levels found both in households and DCCs (p < 0.001). Most of the high lead measurements were found in tiles and playground equipment. Conclusions: Lead exposure estimated from the DCCs, where children spend about 10 h/day, can be as relevant as their household exposure. Therefore, public authorities should render efforts to provide a rigorous surveillance for lead-free painting supplies and for all objects offered to children. (C) 2018 Elsevier Ltd. All rights reserved. (AU)

Processo FAPESP: 15/01395-4 - Níveis sanguíneos de chumbo elevados em pré-escolares: investigação das concentrações do metal em possíveis fontes de exposição
Beneficiário:Júlia Prestes da Rocha Silva
Linha de fomento: Bolsas no Brasil - Iniciação Científica
Processo FAPESP: 12/21840-4 - Exposição a metais não essenciais em São Paulo: níveis sanguíneos em pré-escolares e fatores de risco associados
Beneficiário:Maria Regina Alves Cardoso
Linha de fomento: Auxílio à Pesquisa - Regular
Processo FAPESP: 14/20945-2 - Exposição a chumbo nos ambientes domiciliar e escolar: influência da dieta nas concentrações de chumbo no sangue
Beneficiário:Isabelle Nogueira Leroux
Linha de fomento: Bolsas no Brasil - Iniciação Científica
Processo FAPESP: 11/23272-0 - Exposição a chumbo em São Paulo: níveis sanguíneos em pré-escolares e fatores de risco associados
Beneficiário:Maria Regina Alves Cardoso
Linha de fomento: Auxílio à Pesquisa - Regular