Radiation-related superficial oral mucoceles: An under-recognized acute toxicity in head and neck cancer patients

Autor(es)

Prado-Ribeiro, Ana-Carolina ^{[1, 2]} ; Santos-Silva, Alan-Roger ^[3] ; Faria, Karina-Morais ^[2] ; Silva, Wagner-Gomes ^[2] ; Simonato, Luciana-Estevam ^[1] ; Moutinho, Karina ^[4] ; Brandao, Thais-Bianca ^[2]

Afiliação do(s) autor(es)

^[1] Univ Brasil, Campus Fernandopolis, Sao Paulo - Brazil

^[2] Univ Sao Paulo, Dent Oncol Serv, ICESP, Fac Med, Ave Doutor Arnaldo 251, BR-01246000 Sao Paulo, SP - Brazil

^[3] Univ Campinas UNICAMP, Dept Oral Diag, Semiol Area, Piracicaba Dent Sch, Piracicaba, SP - Brazil

^[4] Univ Sao Paulo, Radiotherapy Serv, ICESP, Fac Med, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: MEDICINA ORAL PATOLOGIA ORAL Y CIRUGIA BUCAL; v. 23, n. 5, p. E518-E523, SEP 1 2018.
• Citações Web of Science: 0

Resumo

Background: Acute toxicity is usually defined as adverse changes occurring immediately or a short time after the start of oncological treatment. Material an Methods: Cross-sectional retrospective study performed with head and neck cancer patients who underwent radiotherapy from 2013 to 2016. Results: Ten (1.2%) patients developed SOMs during radiotherapy, most (80%) of which were men with a mean age of 59.5 years at diagnosis. SOMs mainly affected the floor of the mouth (60%) between the fourth and the sixth weeks of radiation therapy. All lesions were asymptomatic and spontaneously ruptured approximately 9 days after diagnosis. Conclusions: Although rare, SOMs may be regarded as an acute oral toxicity of head and neck radiotherapy. (AU)

• Processo FAPESP: 12/06138-1 - Estudo prospectivo da incidência de trismo induzido por radioterapia em pacientes com carcinoma espinocelular de boca
• Beneficiário: Ana Carolina Prado Ribeiro e Silva
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 13/18402-8 - Avaliação dos efeitos diretos da radiação sobre o esmalte, a dentina e a polpa dental de pacientes com câncer de cabeça e pescoço
• Beneficiário: Alan Roger dos Santos Silva
• Modalidade de apoio: Auxílio à Pesquisa - Regular