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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Radiation-related superficial oral mucoceles: An under-recognized acute toxicity in head and neck cancer patients

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Prado-Ribeiro, Ana-Carolina [1, 2] ; Santos-Silva, Alan-Roger [3] ; Faria, Karina-Morais [2] ; Silva, Wagner-Gomes [2] ; Simonato, Luciana-Estevam [1] ; Moutinho, Karina [4] ; Brandao, Thais-Bianca [2]
Total Authors: 7
[1] Univ Brasil, Campus Fernandopolis, Sao Paulo - Brazil
[2] Univ Sao Paulo, Dent Oncol Serv, ICESP, Fac Med, Ave Doutor Arnaldo 251, BR-01246000 Sao Paulo, SP - Brazil
[3] Univ Campinas UNICAMP, Dept Oral Diag, Semiol Area, Piracicaba Dent Sch, Piracicaba, SP - Brazil
[4] Univ Sao Paulo, Radiotherapy Serv, ICESP, Fac Med, Sao Paulo - Brazil
Total Affiliations: 4
Document type: Journal article
Source: MEDICINA ORAL PATOLOGIA ORAL Y CIRUGIA BUCAL; v. 23, n. 5, p. E518-E523, SEP 1 2018.
Web of Science Citations: 0

Background: Acute toxicity is usually defined as adverse changes occurring immediately or a short time after the start of oncological treatment. Material an Methods: Cross-sectional retrospective study performed with head and neck cancer patients who underwent radiotherapy from 2013 to 2016. Results: Ten (1.2%) patients developed SOMs during radiotherapy, most (80%) of which were men with a mean age of 59.5 years at diagnosis. SOMs mainly affected the floor of the mouth (60%) between the fourth and the sixth weeks of radiation therapy. All lesions were asymptomatic and spontaneously ruptured approximately 9 days after diagnosis. Conclusions: Although rare, SOMs may be regarded as an acute oral toxicity of head and neck radiotherapy. (AU)

FAPESP's process: 12/06138-1 - A prospective study of radiation-induced trismus in patients with oral squamous cell carcinoma
Grantee:Ana Carolina Prado Ribeiro e Silva
Support type: Regular Research Grants
FAPESP's process: 13/18402-8 - Evaluation of the direct effects of radiation on the enamel, dentin and dental pulp of head and neck cancer patients
Grantee:Alan Roger dos Santos Silva
Support type: Regular Research Grants