Univ Sao Paulo, Radiotherapy Serv, ICESP, Fac Med, Sao Paulo - Brazil
Total Affiliations: 4
MEDICINA ORAL PATOLOGIA ORAL Y CIRUGIA BUCAL;
SEP 1 2018.
Web of Science Citations:
Background: Acute toxicity is usually defined as adverse changes occurring immediately or a short time after the start of oncological treatment. Material an Methods: Cross-sectional retrospective study performed with head and neck cancer patients who underwent radiotherapy from 2013 to 2016. Results: Ten (1.2%) patients developed SOMs during radiotherapy, most (80%) of which were men with a mean age of 59.5 years at diagnosis. SOMs mainly affected the floor of the mouth (60%) between the fourth and the sixth weeks of radiation therapy. All lesions were asymptomatic and spontaneously ruptured approximately 9 days after diagnosis. Conclusions: Although rare, SOMs may be regarded as an acute oral toxicity of head and neck radiotherapy. (AU)