| Texto completo | |
| Autor(es): Mostrar menos - |
Gomes Quinhoneiro, Driele Cristina
[1]
;
Nicoletti, Carolina Ferreira
[1]
;
Souza Pinhel, Marcela Augusta
[1]
;
Noronha, Natalia Yumi
[1]
;
Moreno Braga, Camila Bitu
[1]
;
Parenti Oliveira, Bruno Affonso
[1]
;
Cortes-Oliveira, Cristiana
[1]
;
Oliveira, Wanderley Pereira
[2]
;
Salgado Junior, Wilson
[3]
;
Marchini, Julio Sergio
[1]
;
Nonino, Carla Barbosa
[1]
Número total de Autores: 11
|
| Afiliação do(s) autor(es): | [1] Univ Sao Paulo, Ribeirao Preto Med Sch, Dept Internal Med, Ribeirao Preto, SP - Brazil
[2] Univ Sao Paulo, Sch Pharmaceut Sci Ribeirao Preto, Dept Pharmaceut Sci, Ribeirao Preto - Brazil
[3] Univ Sao Paulo, Ribeirao Preto Med Sch, Dept Surg & Anat, Ribeirao Preto - Brazil
Número total de Afiliações: 3
|
| Tipo de documento: | Artigo Científico |
| Fonte: | INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION; v. 69, n. 8, p. 995-1002, NOV 17 2018. |
| Citações Web of Science: | 6 |
| Resumo | |
This study aims (i) to verify expression of the UCPs, PLIN1, PPARG2, and ADRB3 genes in the abdominal subcutaneous adipose tissue of obese women at baseline and after 8 weeks of supplementation with decaffeinated green tea extract, and (ii) to associate findings with clinical parameters. This is a longitudinal study during which 11 women with obesity grade III were submitted to supplementation with 450 mg of (-)-epigallocatechin gallate (EGCG) (intervention group); the control group consisted of 10 eutrophic women. Anthropometric parameters {[}weight, height, and body mass index (BMI)], resting metabolic rate (RMR, measured by indirect calorimetry), and gene expression (measured by real-time PCR, RT-qPCR) were determined before and after supplementation. After 8 weeks, clinical parameters and UCP1, PLIN1, PPARG2, and ADRB3 expression remained unaltered in the intervention group (p > .05). Genetic analysis also showed that the UCP3 gene was upregulated (p = .026), but its upregulation did not promote weight loss. (AU) | |
| Processo FAPESP: | 13/08916-4 - Análise da expressão de genes relacionados ao gasto energético e metabolismo de lipídios de indivíduos com obesidade grau III antes e após intervenções para perda de peso |
| Beneficiário: | Carla Barbosa Nonino |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |
| Processo FAPESP: | 14/00669-0 - Análise da expressão de genes relacionados ao gasto energético e metabolismo de lipídios de indivíduos com obesidade grau III antes e após a suplementação com chá verde |
| Beneficiário: | Driele Cristina Gomes Quinhoneiro |
| Modalidade de apoio: | Bolsas no Brasil - Mestrado |