Data on differentially expressed miRNAs in dogs infected with Leishmania infantum

Autor(es)

Bragato, Jaqueline Poleto ^[1] ; Melo, Larissa Martins ^[1] ; Venturin, Gabriela Lovizutto ^[1] ; Rebech, Gabriela Torres ^[1] ; Garcia, Leandro Encarnacao ^[2] ; Lopes, Flavia Lombardi ^[2] ; Felix de Lima, Valeria Marcal ^[1]

Afiliação do(s) autor(es)

^[1] Sao Paulo State Univ Unesp, Sch Vet Med, Dept Anim Clin Surg & Reprod, Sao Paulo - Brazil

^[2] Sao Paulo State Univ Unesp, Sch Vet Med, Dept Support Prod & Anim Hlth, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: DATA IN BRIEF; v. 17, p. 218-225, APR 2018.
• Citações Web of Science: 1

Resumo

This paper contains data on differentially expressed miRNAs in peripheral blood mononuclear cells (PBMC) of dogs naturally infected by Leishmania (L.) infantum compared to healthy dogs. In recent years, studies with miRNAs have shown that these molecules play a critical role in the regulation and function of immune response.Differentially expressed miRNAs were identified by microarray, validated by real time PCR and compared with parasite load in the dogs. Targets and pathways were analyzed using the Ingenuity Pathway Analysis program. (C) 2018 The Authors. Published by Elsevier Inc. (AU)

• Processo FAPESP: 15/16972-7 - O papel dos miRNA na infecção de células mononucleares de sangue e baço de cão por Leishmania infantum
• Beneficiário: Valéria Marçal Felix de Lima
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 16/02359-4 - O papel dos miRNA na infecção de células mononucleares de sangue periférico e leucócitos esplênicos de cão por Leishmania infantum
• Beneficiário: Jaqueline Poleto Bragato
• Modalidade de apoio: Bolsas no Brasil - Mestrado