Data on differentially expressed miRNAs in dogs infected with Leishmania infantum

Author(s)

Bragato, Jaqueline Poleto ^[1] ; Melo, Larissa Martins ^[1] ; Venturin, Gabriela Lovizutto ^[1] ; Rebech, Gabriela Torres ^[1] ; Garcia, Leandro Encarnacao ^[2] ; Lopes, Flavia Lombardi ^[2] ; Felix de Lima, Valeria Marcal ^[1]

Affiliation

^[1] Sao Paulo State Univ Unesp, Sch Vet Med, Dept Anim Clin Surg & Reprod, Sao Paulo - Brazil

^[2] Sao Paulo State Univ Unesp, Sch Vet Med, Dept Support Prod & Anim Hlth, Sao Paulo - Brazil

• Document type: Journal article
• Source: DATA IN BRIEF; v. 17, p. 218-225, APR 2018.
• Web of Science Citations: 1

Abstract

This paper contains data on differentially expressed miRNAs in peripheral blood mononuclear cells (PBMC) of dogs naturally infected by Leishmania (L.) infantum compared to healthy dogs. In recent years, studies with miRNAs have shown that these molecules play a critical role in the regulation and function of immune response.Differentially expressed miRNAs were identified by microarray, validated by real time PCR and compared with parasite load in the dogs. Targets and pathways were analyzed using the Ingenuity Pathway Analysis program. (C) 2018 The Authors. Published by Elsevier Inc. (AU)

• FAPESP's process: 15/16972-7 - The role of miRNA in Leishmania infantum infection in mononuclear cells and spleen leukocytes from peripheral blood of dog
• Grantee: Valéria Marçal Felix de Lima
• Support Opportunities: Regular Research Grants
• FAPESP's process: 16/02359-4 - The role of miRNA in the infection of peripheral blood mononuclear cells and splenic leukocytes from dog by Leishmania infantum
• Grantee: Jaqueline Poleto Bragato
• Support Opportunities: Scholarships in Brazil - Master