3-Mercaptopropionic acid functionalization of titanium dioxide thin films

Autor(es)

Gomes, Orisson P. ^{[1, 2]} ; Azevedo Neto, Nilton F. ^[1] ; Bronze-Uhle, Erika S. ^{[1, 2]} ; Trino, Luciana D. ^{[1, 2]} ; dos Santos, Cassio M. ^{[1, 2]} ; da Silva, Jose H. D. ^[1] ; Lisboa-Filho, Paulo N. ^{[1, 2]}

Afiliação do(s) autor(es)

^[1] Univ Estadual Paulista, UNESP, Dept Fis, Av Engn Luiz Edmundo Carrijo Coube 14-01, BR-17033360 Bauru, SP - Brazil

^[2] Inst Biomat Tribocorros & Nanomed, Brazilian Branch, Bauru, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Materials Chemistry and Physics; v. 223, p. 32-38, FEB 1 2019.
• Citações Web of Science: 0

Resumo

Nanostructured titanium dioxide (TiO2) films are commonly employed as surface modifiers on medical and dental metallic implants, presenting promising results related to interactions with living tissues, promoting improvements in the in vivo biocorrosion resistance and increased bioactivity when compared to non-coated metallic materials. In addition to these properties, titanium dioxide is also well recognized for its biocompatibility. However, considering the necessary integration with surrounding tissues when this oxide is applied as implant coatings, there are many aspects of the adhesion mechanisms located at the interface between the biological environment and the oxide surface that still need to be addressed. Specifically regarding the surface chemistry, these oxides are mainly terminated by hydroxyl groups (-OH) that are readily functionalized by different molecules, such as the 3-mercaptopropionic acid (MPA). In this contribution, X-ray photoelectron spectroscopy (XPS) and atomic force microscopy (AFM) were used to examine the adsorption of MPA on anatase-and rutile-phase forms of TiO2 thin film surfaces grown by RF magnetron sputtering. According to the obtained results, both anatase and rutile TiO2 films present similarities in roughness and thickness. However, different responses to interaction with the MPA molecules were observed, wherein the functionalization was seen to occur only for the rutile phase. (AU)

• Processo FAPESP: 16/22186-7 - Interação de Proteínas em Superfícies de Filmes Finos de TiO2
• Beneficiário: Orisson Ponce Gomes
• Modalidade de apoio: Bolsas no Brasil - Mestrado
• Processo FAPESP: 13/07296-2 - CDMF - Centro de Desenvolvimento de Materiais Funcionais
• Beneficiário: Elson Longo da Silva
• Modalidade de apoio: Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs
• Processo FAPESP: 14/20471-0 - Filmes finos de óxidos metálicos funcionalizados para estudo da adsorção de proteínas
• Beneficiário: Paulo Noronha Lisboa Filho
• Modalidade de apoio: Auxílio à Pesquisa - Regular