Optical Densitometry Study of the Newly Formed Bone Using rhBMP-2 in Wistar Rat Mandibles

Autor(es)

Joáo Paulo Mardegan Issa ^[1] ; Cássio do Nascimento ^[2] ; Sandra Sato ^[3] ; Rodrigo Edson Santos Barbosa ^[4] ; Emerson Toffanello Benetti ^[5] ; Rubens Ferreira de Albuquerque Junior ^[6]

Afiliação do(s) autor(es)

^[1] University of Sao Paulo. Faculty of Dentistry - Brasil

^[2] University of Sao Paulo. Faculty of Dentistry - Brasil

^[3] University of Sao Paulo. Faculty of Dentistry - Brasil

^[4] University of Sao Paulo. Faculty of Dentistry - Brasil

^[5] University of Sao Paulo. Faculty of Dentistry - Brasil

^[6] University of Sao Paulo. Faculty of Dentistry - Brasil

• Tipo de documento: Artigo Científico
• Fonte: INTERNATIONAL JOURNAL OF MORPHOLOGY; v. 25, n. 2, p. 347-352, 2007-06-00.

Resumo

The purpose of this study was to evaluate the efficacy of monoolein gel as a carrier for rhBMP-2 in the healing bone process of critical bone defects created in Wistar rats mandibles using digitalized radiographic method to analyze this process. In the group 1, the rhBMP-2 was dissolved in aqueous solution and in the group 2, the rhBMP-2 was combined with monoolein gel as a carrier. The results showed that in both of groups it was found efficient bone repair, with a great optical density in the group that the rhBMP-2 was combined with the monoolein gel, but without statistical difference between them (AU)

• Processo FAPESP: 04/12013-0 - Análise do tecido ósseo neoformado sob estímulo da proteína morfogenética rhBMP-2 associada a um novo carreador
• Beneficiário: João Paulo Mardegan Issa
• Modalidade de apoio: Bolsas no Brasil - Mestrado