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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Optical Densitometry Study of the Newly Formed Bone Using rhBMP-2 in Wistar Rat Mandibles

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Author(s):
Joáo Paulo Mardegan Issa [1] ; Cássio do Nascimento [2] ; Sandra Sato [3] ; Rodrigo Edson Santos Barbosa [4] ; Emerson Toffanello Benetti [5] ; Rubens Ferreira de Albuquerque Junior [6]
Total Authors: 6
Affiliation:
[1] University of Sao Paulo. Faculty of Dentistry - Brasil
[2] University of Sao Paulo. Faculty of Dentistry - Brasil
[3] University of Sao Paulo. Faculty of Dentistry - Brasil
[4] University of Sao Paulo. Faculty of Dentistry - Brasil
[5] University of Sao Paulo. Faculty of Dentistry - Brasil
[6] University of Sao Paulo. Faculty of Dentistry - Brasil
Total Affiliations: 6
Document type: Journal article
Source: INTERNATIONAL JOURNAL OF MORPHOLOGY; v. 25, n. 2, p. 347-352, 2007-06-00.
Abstract

The purpose of this study was to evaluate the efficacy of monoolein gel as a carrier for rhBMP-2 in the healing bone process of critical bone defects created in Wistar rats mandibles using digitalized radiographic method to analyze this process. In the group 1, the rhBMP-2 was dissolved in aqueous solution and in the group 2, the rhBMP-2 was combined with monoolein gel as a carrier. The results showed that in both of groups it was found efficient bone repair, with a great optical density in the group that the rhBMP-2 was combined with the monoolein gel, but without statistical difference between them (AU)