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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Pigments in an iridescent bacterium, Cellulophaga fucicola, isolated from Antarctica

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Autor(es):
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Silva, Tiago R. [1, 2] ; Canela-Garayoa, Ramon [3] ; Eras, Jordi [3] ; Rodrigues, Marili V. N. [4] ; dos Santos, Fabio N. [5] ; Eberlin, Marcos N. [5] ; Neri-Numa, Iramaia A. [6] ; Pastore, Glaucia M. [6] ; Tavares, Renata S. N. [7] ; Debonsi, Hosana M. [7] ; Cordeiro, Lorena R. G. [7] ; Rosa, Luiz H. [8] ; Oliveira, Valeria M. [2]
Número total de Autores: 13
Afiliação do(s) autor(es):
[1] Campinas State Univ UNICAMP, Inst Biol, POB 6109, Campinas, SP - Brazil
[2] Univ Estadual Campinas, Div Microbial Resources, Chem Biol & Agr Pluridisciplinary Res Ctr CPQBA, Campinas, SP - Brazil
[3] Univ Lleida, ETSEA, Dept Chem, Agrotecnio Ctr, Lleida - Spain
[4] Univ Estadual Campinas, Dept Organ Chem, Chem Biol & Agr Pluridisciplinary Res Ctr CPQBA, Campinas, SP - Brazil
[5] Campinas State Univ UNICAMP, ThoMSon Mass Spectrometry Lab, Campinas, SP - Brazil
[6] Univ Campinas UNICAMP, Dept Food Sci, Sch Food Engn, Campinas, SP - Brazil
[7] Univ Sao Paulo, Sch Pharmaceut Sci Ribeirao Preto, Ribeirao Preto, SP - Brazil
[8] Univ Fed Minas Gerais, Dept Microbiol, Inst Biol Sci, Belo Horizonte, MG - Brazil
Número total de Afiliações: 8
Tipo de documento: Artigo Científico
Fonte: ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY; v. 112, n. 3, p. 479-490, MAR 2019.
Citações Web of Science: 1
Resumo

An iridescent yellow pigmented bacterium isolated from the Antarctic continent, named Cellulophaga fucicola strain 416, was found to be able to tolerate UV-B radiation. Its crude pigment extract was tested for antioxidant capacity, UV light stability and phototoxicity profile against murine fibroblast lines. The pigments were further isolated and chemically identified by ultra-high-performance liquid chromatography with photodiode array and mass spectrometry detectors. The results showed that the pigment extract presented weak stability under exposure to UV light, a phototoxic profile in the 3t3 Neutral Red Uptake test and a very high antioxidant activity, suggesting that it could be used as food and feed colourants. Zeaxanthin and two isomers of zeaxanthin, -cryptoxanthin and -carotene, were identified using a C18 column. These five carotenoids were the major pigments isolated from C. fucicola 416. In conclusion, the identification of pigments produced by the bacterial strain under study may help us understand how bacteria thrive in high UV and cold environments, and opens avenues for further biotechnological application towards a more sustainable and environmentally friendly way of pigment exploitation. (AU)

Processo FAPESP: 16/05640-6 - Multi-ômicas aplicadas ao conhecimento e exploração de microbiomas Antárticos
Beneficiário:Valeria Maia Merzel
Modalidade de apoio: Auxílio à Pesquisa - Regular
Processo FAPESP: 17/21790-0 - Caracterização química de pigmentos de interesse biotecnológico extraídos de bactérias isoladas da Antártica
Beneficiário:Tiago Rodrigues e Silva
Modalidade de apoio: Bolsas no Exterior - Estágio de Pesquisa - Doutorado
Processo FAPESP: 14/17936-1 - Prospecção de antibióticos e pigmentos a partir de bactérias isoladas da Antártica
Beneficiário:Tiago Rodrigues e Silva
Modalidade de apoio: Bolsas no Brasil - Doutorado