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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

The pyrethroid (+/-)-lambda-cyhalothrin enantioselective biodegradation by a bacterial consortium

Texto completo
Autor(es):
Birolli, Willian G. [1] ; Arai, Marylyn S. [1] ; Nitschke, Marcia [2] ; Porto, Andre L. M. [1]
Número total de Autores: 4
Afiliação do(s) autor(es):
[1] Univ Sao Paulo, Inst Quim Sao Carlos, Lab Quim Organ & Biocatalise, Av Joao Dagnone 1100, Ed Quim Ambiental, BR-13563120 Sao Carlos, SP - Brazil
[2] Univ Sao Paulo, Inst Quim Sao Carlos, Lab Biotecnol Microbiana, Av Joao Dagnone 1100, Ed Quim Ambiental, BR-13563120 Sao Carlos, SP - Brazil
Número total de Afiliações: 2
Tipo de documento: Artigo Científico
Fonte: PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY; v. 156, p. 129-137, MAY 2019.
Citações Web of Science: 2
Resumo

Chiral pesticides have been used in agriculture, including (+/-)-lambda-cyhalothrin ((+/-)-LC), which is a pyrethroid insecticide widely employed on crops for protection against different types of insects. However, enantioselectivity is poorly studied in biodegradation processes. Therefore, the (+/-)-LC enantioselective biodegradation by bacteria from Brazilian savannah was reported in this study with a validated analytical method. All bacterial strains biodegraded (+/-)-LC with different efficiencies. Residual concentrations of LC (3.7-43.1% of biodegradation) and its enantiomeric excesses (0-27% ee) were determined. Additionally, the formation of the main biodegradation metabolite 3-phenoxybenzoic acid was also quantified. A Bacillus consortium composed of the three most efficient strains biodegraded more LC than any isolated strain solely employed in this work, showing that the use of a consortium is an interesting approach. In addition, 13 metabolites were identified and a biodegradation pathway with biochemical reactions of hydrolysis, reduction, esterification, amidation, elimination and group transfer were proposed, confirming the bioremediation potential of these strains. The LC stereoisomer with the highest insecticidal activity (1R,3R,alpha S-enantiomer, also known as gamma-cyhalothrin) was preferentially biodegraded by the studied bacteria. Therefore, crops protection with gamma-cyhalothrin, which can be applied in lower concentrations than (+/-)-LC because it is a more effective product against insects, may also be biodegraded faster than the racemic mixture in the environment, decreasing the toxic effects on non target organisms. (AU)

Processo FAPESP: 14/18257-0 - Novas abordagens em reações biocatalíticas
Beneficiário:Andre Luiz Meleiro Porto
Linha de fomento: Auxílio à Pesquisa - Regular
Processo FAPESP: 14/08558-3 - Biodegradação enantiosseletiva do pesticida piretróide (±)-Lambda-cialotrina por bactérias ambientais
Beneficiário:Marylyn Setsuko Arai
Linha de fomento: Bolsas no Brasil - Iniciação Científica
Processo FAPESP: 12/19934-0 - Biodegradação de pesticidas por micro-organismos (fungos e bactérias)
Beneficiário:Andre Luiz Meleiro Porto
Linha de fomento: Auxílio à Pesquisa - Regular
Processo FAPESP: 17/19721-0 - Emprego de microrganismos ambientais na biodegradação de agrotóxicos estrobilurinicos e piretróides amplamente utilizados na agricultura brasileira
Beneficiário:Willian Garcia Birolli
Linha de fomento: Bolsas no Brasil - Pós-Doutorado