Biodegradable antioxidant chitosan films useful as an anti-aging skin mask

Autor(es)

Afonso, C. R. ^[1] ; Hirano, R. S. ^[1] ; Gaspar, A. L. ^[1] ; Chagas, E. G. L. ^[2] ; Carvalho, R. A. ^[2] ; Silva, F. V. ^[3] ; Leonardi, G. R. ^[4] ; Lopes, P. S. ^[1] ; Silva, C. F. ^[1] ; Yoshida, C. M. P. ^[1]

Afiliação do(s) autor(es)

^[1] UNIFESP Fed Sao Paulo Univ, Inst Environm Chem & Pharmaceut Sci, Sao Paulo, SP - Brazil

^[2] Univ Sao Paulo, Fac Anim Sci & Food Engn, Sao Paulo, SP - Brazil

^[3] UNICAMP State Univ Campinas, Sch Chem Engn, Campinas, SP - Brazil

^[4] UNICAMP State Univ Campinas, Fac Pharm, Campinas, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: International Journal of Biological Macromolecules; v. 132, p. 1262-1273, JUL 1 2019.
• Citações Web of Science: 3

Resumo

Cosmetics, personal care and biomedical products obtained by bio-based polymers and natural bioactive compounds are a new growing market. The ecological awareness is changing consumers' demands, causing consumers to look for more sustainable options, with a reduced environmental impact. The innovation of this work was to develop a natural polymer matrix (chitosan) entrapping antioxidant actives compounds such as annatto (Bixa Orellana L.) and vitamin C with potential application as sustainable anti-aging skin mask treatment. Films of chitosan (Ch) and reacetylated chitosan (RCh), exhibiting different degrees of acetylation (DA = 13.3 and 33.9%, respectively), were produced. The formulations of active films of chitosan (BCh) and reacetylated chitosan (BRCh) were 1% (w/w) of chitosan, 1% (w/w) of annatto powder, 5% (w/w) of vitamin C and 1% (w/w) of glycerol (as plasticizer). Reacetylated chitosan films (DA = 33.9%) presented higher water affinity than chitosan films (DA = 13.3%). The elongation of RCh and BRCh increased and the resistance decreased, as compared to Ch and BCh. The antioxidants compounds (annatto and vitamin C) of BRCh films released faster than BCh films. Thus, the BRCh films showed potential application as an anti-aging skin mask. (C) 2019 Published by Elsevier B.V. (AU)

• Processo FAPESP: 16/21073-4 - Incorporação de inseticidas botânicos em sistemas de embalagens ativas para farináceos
• Beneficiário: Cristiana Maria Pedroso Yoshida
• Modalidade de apoio: Auxílio à Pesquisa - Regular