| Texto completo | |
| Autor(es): |
Laudadio, Gabriele
[1]
;
Bartolomeu, Aloisio de A.
[2, 1]
;
Verwijlen, Lucas M. H. M.
[1]
;
Cao, Yiran
[1]
;
de Oliveira, Kleber T.
;
Noel, Timothy
[1]
Número total de Autores: 6
|
| Afiliação do(s) autor(es): | [1] Eindhoven Univ Technol, Micro Flow Chem & Synthet Methodol, Dept Chem Engn & Chem, Bldg 14 Helix, NL-5600 MB Eindhoven - Netherlands
[2] Univ Fed Sao Carlos, Dept Quim, BR-13565905 Sao Carlos, SP - Brazil
Número total de Afiliações: 2
|
| Tipo de documento: | Artigo Científico |
| Fonte: | Journal of the American Chemical Society; v. 141, n. 30, p. 11832-11836, JUL 31 2019. |
| Citações Web of Science: | 6 |
| Resumo | |
Sulfonyl fluorides are valuable synthetic motifs for a variety of applications, among which sulfur(VI) fluoride exchange-based ``click chemistry{''} is currently the most prominent. Consequently, the development of novel and efficient synthetic methods to access these functional groups is of great interest. Herein, we report a mild and environmentally benign electrochemical approach to prepare sulfonyl fluorides using thiols or disulfides, as widely available starting materials, in combination with KF, as an inexpensive, abundant and safe fluoride source. No additional oxidants nor additional catalysts are required and, due to mild reaction conditions, the reaction displays a broad substrate scope, including a variety of alkyl, benzyl, aryl and heteroaryl thiols or disulfides. (AU) | |
| Processo FAPESP: | 18/08772-6 - Arilação C-H direta de quinolinas, piridinas e estirenos via fotocatálise utilizando sais de arildiazônio e diariliodônio |
| Beneficiário: | Aloisio de Andrade Bartolomeu |
| Modalidade de apoio: | Bolsas no Exterior - Estágio de Pesquisa - Doutorado |