Occupations and the Risk of Head and Neck Cancer A Pooled Analysis of the International Head and Neck Cancer Epidemiology (INHANCE) Consortium

Autor(es):Mostrar menos -

Khetan, Prerna ^[1] ; Boffetta, Paolo ^[1] ; Luce, Daniele ^[2] ; Stucker, Isabelle ^[3] ; Curado, Maria Paula ; Menezes, Ana ^[4] ; Wunsch-Filho, Victor ^[5] ; Ahrens, Wolfgang ^[6] ; Lagiou, Pagona ^[7] ; Serraino, Diego ^[8] ; Richiardi, Lorenzo ^[9] ; Kjaerheim, Kristina ^[10] ; Conway, David ^[11] ; Thomson, Peter ^[12] ; Muscat, Joshua ^[13] ; Mates, Dana ^[14] ; Ramroth, Heribert ^[15] ; Menvielle, Gwenn ^[16] ; Vaughan, Thomas L. ^[17] ; Brenner, Hermann ^{[18, 19, 20, 21]} ; Lee, Yuan-Chin Amy ^{[22, 23]} ; La Vecchia, Carlo ^[24] ; Hashibe, Mia ^{[22, 23]} ; Hashim, Dana ^[1]

Afiliação do(s) autor(es):Mostrar menos -

^[1] Icahn Sch Med Mt Sinai, Tisch Canc Inst, New York, NY 10029 - USA

^[2] Univ Rennes, Natl Inst Hlth & Med Res, Sch Adv Studies Publ Hlth, Inst Hlth Environm & Work Res, Res Unit UMR S 1085, Pointe A Pitre, Guadeloupe - France

^[3] Paris Saclay Univ, Paris Sud Univ, Canc & Environm Team CESP, Natl Inst Hlth & Med Res U1018, INSERM, Villejuif - France

^[4] Univ Fed Pelotas, Pelotas - Brazil

^[5] Univ Sao Paulo, Sao Paulo - Brazil

^[6] Bremen Inst Prevent Res & Social Med, Leibniz Inst Prevent Res & Epidemiol, Bremen - Germany

^[7] Univ Athens, Sch Med, Athens - Greece

^[8] Oncol Reference Ctr, Inst Sci Characterizat & Hospitalizat, Aviano - Italy

^[9] Univ Turin, Dept Med Sci, Turin - Italy

^[10] Inst Populat Based Canc Res, Cancer Registry Norway, Oslo - Norway

^[11] Univ Glasgow, Coll Med Vet & Life Sci, Sch Med Dent & Nursing, Glasgow, Lanark - Scotland

^[12] Univ Hong Kong, Hong Kong - Peoples R China

^[13] Penn State Coll Med, Hershey, PA - USA

^[14] Natl Inst Publ Hlth, Bucharest - Romania

^[15] Heidelberg Univ, Heidelberg - Germany

^[16] Sorbonne Univ, Pierre Louis Inst Epidemiol & Publ Hlth, Natl Inst Hlth & Med Res, Paris - France

^[17] Fred Hutchinson Canc Res Ctr, 1124 Columbia St, Seattle, WA 98104 - USA

^[18] German Canc Res Ctr, Div Clin Epidemiol & Aging Res, Heidelberg - Germany

^[19] German Canc Res Ctr, German Canc Consortium, Heidelberg - Germany

^[20] German Canc Res Ctr, Div Prevent Oncol, Heidelberg - Germany

^[21] Natl Ctr Tumor Dis, Heidelberg - Germany

^[22] Univ Utah, Sch Med, Dept Family & Prevent Med, Div Publ Hlth, Salt Lake City, UT 84112 - USA

^[23] Univ Utah, Sch Med, Huntsman Canc Inst, Salt Lake City, UT - USA

^[24] Univ Milan, Dept Clin Sci & Community Hlth, Milan - Italy

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE; v. 61, n. 5, p. 397-404, MAY 2019.
• Citações Web of Science: 0

Resumo

Objective: To investigate the associations between head and neck cancer (HNC) risk and occupations. Methods: We harmonized data on occupations in a pooled analysis of 8839 HNC cases and 13,730 controls in International Head and Neck Cancer Epidemiology (INHANCE) consortium. Logistic regression was used to estimate odds ratios (ORs) for associations of occupations and HNC risk. Population attributable fraction (PAF) for occupations was calculated using the formula P-EC x (OR - 1)/OR.(1) Results: Trend of increasing HNC risk was found with increasing duration of employment for many occupations, including cooks (OR = 1.36; 95% confidence interval {[}CI] 1.09 to 1.68), cleaners (OR = 1.38; 95% CI 1.13 to 1.69), painters (OR = 1.82; 95% CI 1.42 to 2.35). The PAF for a priori occupations was 14.5% (95% CI 7.1% to 21.9%) for HNC. Conclusions: We found associations between certain occupations and HNC risks, including for subsites, with a duration-response relationship. (AU)

• Processo FAPESP: 01/01768-2 - Estudo internacional de fatores ambientais, vírus e câncer de cavidade oral e de laringe
• Beneficiário: José Eluf Neto
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 10/51168-0 - Fatores ambientais, clínicos, histopatológicos e moleculares associados ao desenvolvimento e ao prognóstico de carcinomas epidermoides de cabeça e pescoço
• Beneficiário: Eloiza Helena Tajara da Silva
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Processo FAPESP: 04/12054-9 - Busca de marcadores de agressividade em tumores de cabeça e pescoço
• Beneficiário: Eloiza Helena Tajara da Silva
• Modalidade de apoio: Auxílio à Pesquisa - Temático