Entropy Analysis of High-Definition Transcranial Electric Stimulation Effects on EEG Dynamics

Autor(es)

Nascimento, Diego C. ^[1] ; Depetri, Gabriela ^[1] ; Stefano, Luiz H. ^[2] ; Anacleto, Osvaldo ^[1] ; Leite, Joao P. ^[2] ; Edwards, Dylan J. ^{[3, 4]} ; Santos, Taiza E. G. ^[2] ; Louzada Neto, Francisco ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Inst Math Sci & Comp, BR-13566590 Sao Carlos, SP - Brazil

^[2] Univ Sao Paulo, Ribeirao Preto Med Sch, BR-14049900 Ribeirao Preto - Brazil

^[3] Moss Rehabil Res Inst, Elkins Pk, PA 19027 - USA

^[4] Edith Cowan Univ, Sch Med & Hlth Sci, Joondalup, WA 6027 - Australia

• Tipo de documento: Artigo Científico
• Fonte: BRAIN SCIENCES; v. 9, n. 8 AUG 2019.
• Citações Web of Science: 0

Resumo

A foundation of medical research is time series analysis-the behavior of variables of interest with respect to time. Time series data are often analyzed using the mean, with statistical tests applied to mean differences, and has the assumption that data are stationary. Although widely practiced, this method has limitations. Here we present an alternative statistical approach with sample analysis that provides a summary statistic accounting for the non-stationary nature of time series data. This work discusses the use of entropy as a measurement of the complexity of time series, in the context of Neuroscience, due to the non-stationary characteristic of the data. To elucidate our argument, we conducted entropy analysis on a sample of electroencephalographic (EEG) data from an interventional study using non-invasive electrical brain stimulation. We demonstrated that entropy analysis could identify intervention-related change in EEG data, supporting that entropy can be a useful ``summary{''} statistic in non-linear dynamical systems. (AU)

• Processo FAPESP: 13/07375-0 - CeMEAI - Centro de Ciências Matemáticas Aplicadas à Indústria
• Beneficiário: José Alberto Cuminato
• Linha de fomento: Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs