Assessment of Novel C-4 Methylated Tetraketide by HPLC-SPE-TT in Saccharicola sp., an Endophytic Fungus in Eugenia jambolana Lam.

Autor(es)

Maiara S. Borges ^[1] ; Carolina R. Biasetto ^[2] ; Vanessa M. Chapla ^[3] ; Samad N. Ebrahimi ^[4] ; Mayra F. Costa ^[5] ; Vanderlan S. Bolzani ^[6] ; Angela R. Araujo ^[7]

Afiliação do(s) autor(es)

^[1] Universidade Estadual Paulista (Unesp). Instituto de Química - Brasil

^[2] Universidade Estadual Paulista (Unesp). Instituto de Química - Brasil

^[3] Universidade Federal do Tocantins (UFT) - Brasil

^[4] Shahid Beheshti University. Drugs Research Institute. Department of Phytochemistry, Medicinal Plants - Irã

^[5] Universidade Estadual Paulista (Unesp). Instituto de Química - Brasil

^[6] Universidade Estadual Paulista (Unesp). Instituto de Química - Brasil

^[7] Universidade Estadual Paulista (Unesp). Instituto de Química - Brasil

• Tipo de documento: Artigo Científico
• Fonte: Journal of the Brazilian Chemical Society; v. 30, n. 3, p. 522-527, 2019-03-00.

Resumo

A new compound named methyl (6S,7S,2E,4E)-6,7-dihydroxy-4,6-dimethyl octanoate was isolated from Saccharicola sp. using high performance liquid chromatography-solid phase extraction-transfer tube (HPLC-SPE-TT), together with four known compounds, fusaric acid, trans-4-hydroxymellein, thymidine and adenosine. Saccharicola sp. was isolated from the stems of Eugenia jambolana Lam. (Myrtaceae) as endophytic fungus. The structure of this novel substance was established based on its spectroscopic data, including 1H and 13C nuclear magnetic resonance (NMR), 2D NMR techniques and high-resolution electrospray ionization mass spectrometry (HR-ESI-MS). This paper deals with the first report of its kind on this compound in Saccharicola sp. (AU)

• Processo FAPESP: 14/50926-0 - INCT 2014: biodiversidade e produtos naturais
• Beneficiário: Vanderlan da Silva Bolzani
• Modalidade de apoio: Auxílio à Pesquisa - Programa BIOTA - Temático
• Processo FAPESP: 13/07600-3 - CIBFar - Centro de Inovação em Biodiversidade e Fármacos
• Beneficiário: Glaucius Oliva
• Modalidade de apoio: Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs