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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Assessment of Novel C-4 Methylated Tetraketide by HPLC-SPE-TT in Saccharicola sp., an Endophytic Fungus in Eugenia jambolana Lam.

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Author(s):
Maiara S. Borges [1] ; Carolina R. Biasetto [2] ; Vanessa M. Chapla [3] ; Samad N. Ebrahimi [4] ; Mayra F. Costa [5] ; Vanderlan S. Bolzani [6] ; Angela R. Araujo [7]
Total Authors: 7
Affiliation:
[1] Universidade Estadual Paulista (Unesp). Instituto de Química - Brasil
[2] Universidade Estadual Paulista (Unesp). Instituto de Química - Brasil
[3] Universidade Federal do Tocantins (UFT) - Brasil
[4] Shahid Beheshti University. Drugs Research Institute. Department of Phytochemistry, Medicinal Plants - Irã
[5] Universidade Estadual Paulista (Unesp). Instituto de Química - Brasil
[6] Universidade Estadual Paulista (Unesp). Instituto de Química - Brasil
[7] Universidade Estadual Paulista (Unesp). Instituto de Química - Brasil
Total Affiliations: 7
Document type: Journal article
Source: Journal of the Brazilian Chemical Society; v. 30, n. 3, p. 522-527, 2019-03-00.
Abstract

A new compound named methyl (6S,7S,2E,4E)-6,7-dihydroxy-4,6-dimethyl octanoate was isolated from Saccharicola sp. using high performance liquid chromatography-solid phase extraction-transfer tube (HPLC-SPE-TT), together with four known compounds, fusaric acid, trans-4-hydroxymellein, thymidine and adenosine. Saccharicola sp. was isolated from the stems of Eugenia jambolana Lam. (Myrtaceae) as endophytic fungus. The structure of this novel substance was established based on its spectroscopic data, including 1H and 13C nuclear magnetic resonance (NMR), 2D NMR techniques and high-resolution electrospray ionization mass spectrometry (HR-ESI-MS). This paper deals with the first report of its kind on this compound in Saccharicola sp. (AU)

FAPESP's process: 13/07600-3 - CIBFar - Center for Innovation in Biodiversity and Drug Discovery
Grantee:Glaucius Oliva
Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC
FAPESP's process: 14/50926-0 - INCT 2014: biodiversity and natural products
Grantee:Vanderlan da Silva Bolzani
Support Opportunities: BIOTA-FAPESP Program - Thematic Grants