| Texto completo | |
| Autor(es): |
Soares, Ciro Dantas
[1]
;
Carlos, Roman
[2]
;
Diaz Molina, Juan Pablo
[2]
;
de Lima Morais, Thayna Melo
[1]
;
de Almeida, Oslei Paes
[1]
Número total de Autores: 5
|
| Afiliação do(s) autor(es): | [1] Univ Campinas UNICAMP, Piracicaba Dent Sch, Oral Pathol, Av Limeira 901, POB 52, BR-13414903 Piracicaba, SP - Brazil
[2] Hosp Herrera Llerandi, Ctr Clinico Cabeza & Cuello, Guatemala City - Guatemala
Número total de Afiliações: 2
|
| Tipo de documento: | Artigo Científico |
| Fonte: | Head and Neck Pathology; v. 13, n. 4, p. 722-726, DEC 2019. |
| Citações Web of Science: | 0 |
| Resumo | |
Smooth muscle tumors associated with Epstein-Barr virus infections (EBV-SMT) of laryngeal origin are exceedingly rare and have been reported in few adult patients, but not in children. This reported case describes a lesion found in the larynx of an 8-year-old Guatemalan undernourished girl. Microscopically, the lesion showed a highly cellular mesenchymal spindle cell tumor, containing frequent lymphocytes. The immunohistochemical analysis revealed positivity for alpha-smooth muscle actin and h-caldesmon. In addition, most of the tumor cells were positive for EBV by in situ hybridization. To the best of the author's knowledge, this is the first literature-reported case of laryngeal EBV-SMT occurring in an undernourished child. (AU) | |
| Processo FAPESP: | 15/25905-1 - Expressão de Akt, COX-2, RUNX1 e metaloproteinases em melanomas metastáticos e Prospecção biotecnológica de moléculas com atividade antitumoral |
| Beneficiário: | Ciro Dantas Soares |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado |