| Texto completo | |
| Autor(es): |
de Lima Nascimento, Tatiana Rita
[1]
;
de Amoedo Campos Velo, Marilia Mattar
[2]
;
Silva, Camila Felix
[1]
;
Silva Costa Cruz, Sara Brito
[1]
;
Cavalcanti Gondim, Brenna Louise
[1, 3]
;
Lia Mondelli, Rafael Francisco
[2]
;
Cancado Castellano, Lucio Roberto
[1]
Número total de Autores: 7
|
| Afiliação do(s) autor(es): | [1] Univ Fed Paraiba, Tech Sch Hlth UFPB, Human Immunol Res & Educ Grp GEPIH, Joao Pessoa, Paraiba - Brazil
[2] Univ Sao Paulo, Bauru Sch Dent, Dept Operat Dent Endodont & Dent Mat, Sao Paulo, SP - Brazil
[3] State Univ Paraiba, Dept Dent, Postgrad Program Dent, Campina Grande, Paraiba - Brazil
Número total de Afiliações: 3
|
| Tipo de documento: | Artigo de Revisão |
| Fonte: | CURRENT PHARMACEUTICAL DESIGN; v. 25, n. 37, p. 3997-4012, 2019. |
| Citações Web of Science: | 0 |
| Resumo | |
Background: The high surface-to-volume ratio of polymeric nanofibers makes them an effective vehicle for the release of bioactive molecules and compounds such as growth factors, drugs, herbal extracts and gene sequences. Synthetic polymers are commonly used as sensors, reinforcements and energy storage, whereas natural polymers are more prone to mimicking an extracellular matrix. Natural polymers are a renewable resource and classified as an environmentally friendly material, which might be used in different techniques to produce nanofibers for biomedical applications such as tissue engineering, implantable medical devices, antimicrobial barriers and wound dressings, among others. This review sheds some light on the advantages of natural over synthetic polymeric materials for nanofiber production. Also, the most important techniques employed to produce natural nanofibers are presented. Moreover, some pieces of evidence regarding toxicology and cell-interactions using natural nanofibers are discussed. Clearly, the potential extrapolation of such laboratory results into human health application should be addressed cautiously. (AU) | |
| Processo FAPESP: | 19/06045-2 - Síntese e caracterização físico-química de um biopolímero de mantas de nanofibras (Cotton wool-like) de óxido de grafeno |
| Beneficiário: | Rafael Francisco Lia Mondelli |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |