Diversity of human papillomavirus typing among women population living in rural and remote areas of Brazilian territory

Autor(es)

Lorenzi, Adriana Tarla ^{[1, 2]} ; Fregnani, Jose Humberto ^{[1, 3]} ; Villa, Luisa Lina ^{[4, 5]} ; Sichero, Laura ^[4] ; Nunes, Emily Montosa ^[4] ; Longatto-Filho, Adhemar ^{[6, 1, 7, 8]}

Afiliação do(s) autor(es)

^[1] Barretos Canc Hosp, Pio XII Fdn, Mol Oncol Res Ctr, Teaching & Res Inst, Barretos - Brazil

^[2] Alfredo Nasser Fac UNIFAN, Fac Med, Goiania, Go - Brazil

^[3] AC Camargo Canc Ctr, Educ, Sao Paulo, SP - Brazil

^[4] ICESP, Ctr Translat Res Oncol, Mol Biol Lab, Sao Paulo, SP - Brazil

^[5] Univ Sao Paulo, Sch Med, Dept Radiol & Oncol, Sao Paulo, SP - Brazil

^[6] Univ Sao Paulo, Fac Med, Dept Pathol, Med Lab Med Invest LIM 14, Sao Paulo, SP - Brazil

^[7] Univ Minho, Sch Med, Res Inst Life & Hlth Sci ICVS, Braga - Portugal

^[8] ICVS 3Bs Associated Lab Govt Portugal, Braga, Guimaraes - Portugal

• Tipo de documento: Artigo Científico
• Fonte: PAPILLOMAVIRUS RESEARCH; v. 8, DEC 2019.
• Citações Web of Science: 0

Resumo

Objectives: Genotyping HPV from samples tested positive to careHPV (TM) assay in rural and remote areas of Brazilian territory. Methods: A total of 5079 women were enrolled in an opportunistic screening from the Barretos Cancer Hospital, through mobile units or ambulatory unit. All careHPV (TM) hr-HPV positive samples were tested by a Luminex-based protocol in order to evaluate the HPV infecting types. Results: Positive hr-HPV results were obtained in 10.6% (536/5068) of women. Among these cases, HPV-56 and HPV-51 were the most common types detected in 32.3% and 31.4%, respectively. HPV-53 (20.5%), HPV-18 (18.5%), HPV-58 (17.6%), HPV-52 (16.0%) and HPV-16.6%) were the other most frequent types detected. These frequencies represent prevalences of 2.35%, 2.12%, 2.02%, 1.84% and 1.80% respectively, within the population studied. Regarding low-risk HPVs, HPV-6 was detected in 12.9% of the samples. The less frequent types (< 3%) were: HPV-70, HPV-11 and HPV-26. Conclusions: The most frequent types detected were: HPV-56, HPV-51, HPV-53, HPV-18, HPV-58, HPV-52 and HPV-16 according to decreasing rates. (AU)

• Processo FAPESP: 08/57889-1 - Instituto de Ciência e Tecnologia para o Estudo das Doenças Associadas ao Papilomavírus
• Beneficiário: Luisa Lina Villa
• Modalidade de apoio: Auxílio à Pesquisa - Temático