Effects of Sleep Deprivation on Acute Skeletal Muscle Recovery after Exercise

Autor(es)

Dattilo, Murilo ^[1] ; Moreira Antunes, Hanna Karen ^[2] ; Nunes Galbes, Nadine Marques ^[3] ; Monico-Neto, Marcos ^[1] ; Souza, Helton De Sa ^[1] ; Lucio Dos Santos Quaresma, Marcus Vinicius ^[1] ; Lee, Kil Sun ^[4] ; Ugrinowitsch, Carlos ^[5] ; Tufik, Sergio ^[1] ; De Mello, Marco Tulio ^[6]

Afiliação do(s) autor(es)

^[1] Univ Fed Sao Paulo, Dept Psychobiol, Sao Paulo - Brazil

^[2] Univ Fed Sao Paulo, Dept Biosci, Santos, SP - Brazil

^[3] Univ Sao Paulo, Fac Publ Hlth, Sao Paulo - Brazil

^[4] Univ Fed Sao Paulo, Dept Biochem, Sao Paulo - Brazil

^[5] Univ Sao Paulo, Sch Phys Educ & Sport, Sao Paulo - Brazil

^[6] Univ Fed Minas Gerais, Sch Phys Educ, Belo Horizonte, MG - Brazil

• Tipo de documento: Artigo Científico
• Fonte: MEDICINE AND SCIENCE IN SPORTS AND EXERCISE; v. 52, n. 2, p. 507-514, FEB 2020.
• Citações Web of Science: 0

Resumo

Purpose Sleep is considered essential for muscle recovery, mainly due to its effect on hormone secretion. Total sleep deprivation or restriction is known to alter not only blood hormones but also cytokines that might be related to skeletal muscle recovery. This study aimed to evaluate whether total sleep deprivation after eccentric exercise-induced muscle damage (EEIMD) modifies the profiles of blood hormones and cytokines. Methods In two separate conditions, with a crossover and randomized model, 10 men (age, 24.5 2.9 yr; body mass index, 22.7 2.3 kg.m(-2)) performed a unilateral EEIMD protocol that comprised 240 eccentric contractions of the knee extensor muscles using an isokinetic dynamometer. In one condition, a ``muscle damage{''} protocol was followed by 48 h of total sleep deprivation and 12 h of normal sleep (DEPRIVATION). In the other condition, the same muscle damage protocol was conducted, followed by three nights of regular sleep (SLEEP). Isometric muscle voluntary contraction tests and blood samples were collected serially throughout the protocol and analyzed for creatine kinase, free and total testosterone, IGF-1, cortisol, tumor necrosis factor-alpha, interleukin (IL)-1beta, IL-6, receptor antagonist of IL-1 and IL-10. Results Muscle voluntary contraction and serum creatine kinase increased equally over the study period in both conditions. From the cytokines evaluated, only IL-6 increased in DEPRIVATION. No differences were detected in testosterone levels between conditions, but IGF-1, cortisol, and cortisol/total testosterone ratio were higher in DEPRIVATION. Conclusions Total sleep deprivation after EEIMD does not delay muscle strength recovery but modifies inflammatory and hormonal responses. (AU)

• Processo FAPESP: 98/14303-3 - Center for Sleep Studies
• Beneficiário: Sergio Tufik
• Modalidade de apoio: Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs
• Processo FAPESP: 10/07005-0 - Efeitos da privação de sono no processo de recuperação muscular
• Beneficiário: Marco Túlio de Mello
• Modalidade de apoio: Auxílio à Pesquisa - Regular