A Transfer Entropy Approach for the Assessment of the Impact of Inspiratory Muscle Training on the Cardiorespiratory Coupling of Amateur Cyclists

Autor(es)

de Abreu, Raphael Martins ^[1] ; Catai, Aparecida Maria ^[1] ; Cairo, Beatrice ^[2] ; Rehder-Santos, Patricia ^[1] ; da Silva, Claudio Donisete ^[1] ; Signini, Etore De Favari ^[1] ; Sakaguchi, Camila Akemi ^[1] ; Porta, Alberto ^{[3, 2]}

Afiliação do(s) autor(es)

^[1] Univ Fed Sao Carlos, Dept Phys Therapy, Sao Carlos - Brazil

^[2] Univ Milan, Dept Biomed Sci Hlth, Milan - Italy

^[3] IRCCS Policlin San Donato, Dept Cardiothorac Vasc Anesthesia & Intens Care, Milan - Italy

• Tipo de documento: Artigo Científico
• Fonte: FRONTIERS IN PHYSIOLOGY; v. 11, FEB 25 2020.
• Citações Web of Science: 0

Resumo

The strength of cardiorespiratory interactions diminishes with age. Physical exercise can reduce the rate of this trend. Inspiratory muscle training (IMT) is a technique capable of improving cardiorespiratory interactions. This study evaluates the effect of IMT on cardiorespiratory coupling in amateur cyclists. Thirty male young healthy cyclists underwent a sham IMT of very low intensity (SHAM, n = 9), an IMT of moderate intensity at 60% of the maximal inspiratory pressure (MIP60, n = 10) and an IMT of high intensity at the critical inspiratory pressure (CIP, n = 11). Electrocardiogram, non-invasive arterial pressure, and thoracic respiratory movement (RM) were recorded before (PRE) and after (POST) training at rest in supine position (REST) and during active standing (STAND). The beat-to-beat series of heart period (HP) and systolic arterial pressure (SAP) were analyzed with the RM signal via a traditional non-causal approach, such as squared coherence function, and via a causal model-based transfer entropy (TE) approach. Cardiorespiratory coupling was quantified via the HP-RM squared coherence at the respiratory rate (K-HP-R(M)2), the unconditioned TE from RM to HP (TERM -> HP) and the TE from RM to HP conditioned on SAP (TERM -> HP| SAP). In PRE condition we found that STAND led to a decrease of TERM -> HP| SAP. After SHAM and CIP training this tendency was confirmed, while MIP60 inverted it by empowering cardiorespiratory coupling. This behavior was observed in presence of unvaried SAP mean and with usual responses of the baroreflex control and HP mean to STAND. TERM -> HP and K-HP-(RM)2 were not able to detect the post-training increase of cardiorespiratory coupling strength during STAND, thus suggesting that conditioning out SAP is important for the assessment of cardiorespiratory interactions. Since the usual response of HP mean, SAP mean and baroreflex sensitivity to postural stressor were observed after MIP60 training, we conclude that the post-training increase of cardiorespiratory coupling during STAND in MIP60 group might be the genuine effect of some rearrangements at the level of central respiratory network and its interactions with sympathetic drive and vagal activity. (AU)

• Processo FAPESP: 17/13402-0 - Comparação de diferentes intensidades de treinamento muscular inspiratório sobre o controle autonômico cardiovascular de ciclistas: estudo clínico controlado e randomizado
• Beneficiário: Raphael Martins de Abreu
• Modalidade de apoio: Bolsas no Brasil - Doutorado Direto
• Processo FAPESP: 18/11123-0 - Análise inovadora do controle autonômico cardiovascular em ciclistas após diferentes intensidades de treinamento muscular inspiratório: estudo clínico controlado e aleatorizado
• Beneficiário: Raphael Martins de Abreu
• Modalidade de apoio: Bolsas no Exterior - Estágio de Pesquisa - Doutorado Direto
• Processo FAPESP: 16/22215-7 - Impacto do treinamento muscular inspiratório e do envelhecimento no mapeamento metabólico, modulação autonômica e respostas cardiovasculares, respiratórias e metabólicas e predição da saúde cardiorrespiratória por meio de wearables
• Beneficiário: Aparecida Maria Catai
• Modalidade de apoio: Auxílio à Pesquisa - Temático