Recent Trends in Biomaterials for Immobilization of Lipases for Application in Non-Conventional Media

Autor(es)

Alnoch, Robson Carlos ^{[1, 2]} ; dos Santos, Leandro Alves ^[3] ; de Almeida, Janaina Marques ^[2] ; Krieger, Nadia ^[3] ; Mateo, Cesar ^[4]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Fac Filosofia Ciencias & Letras Ribeirao Preto, Dept Biol, BR-14040900 Ribeirao Preto, SP - Brazil

^[2] Univ Fed Parana, Ctr Politecn, Dept Bioquim & Biol Mol, Cx P 19081, BR-81531980 Curitiba, Parana - Brazil

^[3] Univ Fed Parana, Ctr Politecn, Dept Quim, Cx P 19061, BR-81531980 Curitiba, Parana - Brazil

^[4] Inst Catalisis & Petroleoquim CSIC, Dept Biocatalisis, Marie Curie 2, Campus UAM, Madrid 28049 - Spain

• Tipo de documento: Artigo de Revisão
• Fonte: CATALYSTS; v. 10, n. 6 JUN 2020.
• Citações Web of Science: 0

Resumo

The utilization of biomaterials as novel carrier materials for lipase immobilization has been investigated by many research groups over recent years. Biomaterials such as agarose, starch, chitin, chitosan, cellulose, and their derivatives have been extensively studied since they are non-toxic materials, can be obtained from a wide range of sources and are easy to modify, due to the high variety of functional groups on their surfaces. However, although many lipases have been immobilized on biomaterials and have shown potential for application in biocatalysis, special features are required when the biocatalyst is used in non-conventional media, for example, in organic solvents, which are required for most reactions in organic synthesis. In this article, we discuss the use of biomaterials for lipase immobilization, highlighting recent developments in the synthesis and functionalization of biomaterials using different methods. Examples of effective strategies designed to result in improved activity and stability and drawbacks of the different immobilization protocols are discussed. Furthermore, the versatility of different biocatalysts for the production of compounds of interest in organic synthesis is also described. (AU)

• Processo FAPESP: 20/00081-4 - Desenvolvimento de estratégias para imobilização e co-imobilização de enzimas envolvidas na degradação de biomassa
• Beneficiário: Robson Carlos Alnoch
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado
• Processo FAPESP: 18/07522-6 - Desenvolvimento de tecnologias ecológicas para a hidrólise de biomassa e resíduos da indústria de celulose e papel
• Beneficiário: Maria de Lourdes Teixeira de Moraes Polizeli
• Modalidade de apoio: Auxílio à Pesquisa - Regular