Topical application of lidocaine or bupivacaine in the healing of surgical wounds in dogs

Autor(es)

Bruno Watanabe Minto ^[1] ; Laura Zanato ^[2] ; Guilherme Galhardo Franco ^[3] ; Fernando Yoiti Kitamura Kawamoto ^[4] ; Camila Potério Borsaro ^[5] ; Josiane Morais Pazzini ^[6] ; Elizabeth Regina Carvalho ^[7] ; Andresa Matsui ^[8]

Afiliação do(s) autor(es)

^[1] Universidade Estadual Paulista. Faculdade de Ciências Agrárias e Veterinárias. Department of Clinical and Veterinary Surgery - Brasil

^[2] FCAV-UNESP - Brasil

^[3] FCAV-UNESP. Postgraduate Program in Veterinary Surgery - Brasil

^[4] FCAV-UNESP. Postgraduate Program in Veterinary Surgery - Brasil

^[5] FCAV-UNESP. Postgraduate Program in Veterinary Surgery - Brasil

^[6] União das Faculdades dos Grandes Lagos - Brasil

^[7] FCAV-UNESP. Postgraduate Program in Veterinary Surgery - Brasil

^[8] FCAV-UNESP. Postgraduate Program in Veterinary Surgery - Brasil

• Tipo de documento: Artigo Científico
• Fonte: Acta Cirurgica Brasileira; v. 35, n. 7 2020-08-14.

Resumo

Abstract Purpose: To analyze the anesthetic drugs interference with wound healing when used in the surgical bed. Methods: Macro and microscopic aspects of healing of surgical wounds were evaluated after instillation of topical anesthetics without vasoconstrictor or saline solution 0.9% as control in the transsurgical period. Thirty dogs, males and females were divided into two experimental groups. In both groups, two circular punch lesions of 6 mm diameter were performed in the abdomen. In group 1, lidocaine was instilled in one of the lesions and saline solution in the contralateral lesion. In group 2 the procedure was repeated with the use of bupivacaine. The macroscopic assessment of the lesions was performed on the first, third and tenth postoperative day. The excisional biopsy was performed on the tenth day and the samples were submitted for histopathological examination. Results: The macroscopic analysis had a significant difference between groups. Microscopic analysis was not significant between groups. Conclusions: The topical application of lidocaine and bupivacaine in the surgical wound is feasible and it does not influence skin healing. The benefit of such a practice, which has been the subject of other studies, seems to outweigh the risks. (AU)

• Processo FAPESP: 15/24955-5 - Avaliação da aplicação tópica de lidocaína ou bupivacaína na cicatrização de feridas cirúrgicas em cães
• Beneficiário: Laura Zanato
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica