Transcriptomic Analysis of Four Cerianthid (Cnidaria, Ceriantharia) Venoms

Autor(es)

Klompen, Anna M. L. ^[1] ; Macrander, Jason ^{[2, 3]} ; Reitzel, Adam M. ^[2] ; Stampar, Sergio N. ^[4]

Afiliação do(s) autor(es)

^[1] Univ Kansas, Dept Ecol & Evolutionary Biol, 1200 Sunnyside Ave, Lawrence, KS 66045 - USA

^[2] Univ North Carolina Charlotte, Dept Biol Sci, 9201 Univ City Blvd, Charlotte, NC 28262 - USA

^[3] Florida Southern Coll, Dept Biol, 111 Lake Hollingsworth Dr, Lakeland, FL 33801 - USA

^[4] Univ Estadual Paulista, UNESP, Dept Biol Sci, FCL, BR-19806 Assis, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: MARINE DRUGS; v. 18, n. 8 AUG 2020.
• Citações Web of Science: 0

Resumo

Tube anemones, or cerianthids, are a phylogenetically informative group of cnidarians with complex life histories, including a pelagic larval stage and tube-dwelling adult stage, both known to utilize venom in stinging-cell rich tentacles. Cnidarians are an entirely venomous group that utilize their proteinaceous-dominated toxins to capture prey and defend against predators, in addition to several other ecological functions, including intraspecific interactions. At present there are no studies describing the venom for any species within cerianthids. Given their unique development, ecology, and distinct phylogenetic-placement within Cnidaria, our objective is to evaluate the venom-like gene diversity of four species of cerianthids from newly collected transcriptomic data. We identified 525 venom-like genes between all four species. The venom-gene profile for each species was dominated by enzymatic protein and peptide families, which is consistent with previous findings in other cnidarian venoms. However, we found few toxins that are typical of sea anemones and corals, and furthermore, three of the four species express toxin-like genes closely related to potent pore-forming toxins in box jellyfish. Our study is the first to provide a survey of the putative venom composition of cerianthids and contributes to our general understanding of the diversity of cnidarian toxins. (AU)

• Processo FAPESP: 15/24408-4 - Evolução e diversidade de Ceriantharia (Cnidaria)
• Beneficiário: Sérgio Nascimento Stampar
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 17/50028-0 - Effects of diet and diel lighting on expression of venom diversity in two species of tube dwelling anemone
• Beneficiário: Sérgio Nascimento Stampar
• Modalidade de apoio: Auxílio à Pesquisa - Regular
• Processo FAPESP: 19/03552-0 - Padrões reprodutivos, comportamentais e genômicos em Ceriantharia (Cnidaria): um passo para a compreensão da evolução marinha
• Beneficiário: Sérgio Nascimento Stampar
• Modalidade de apoio: Auxílio à Pesquisa - Regular