A New Approach for the Production of Selenium-Enriched and Probiotic Yeast Biomass from Agro-Industrial by-Products in a Stirred-Tank Bioreactor

Autor(es)

Martiniano, Sabrina Evelin ^[1] ; Fernandes, Leticia Alves ^[1] ; Alba, Edith Mier ^[1] ; Philippini, Rafael Rodrigues ^[1] ; Tabuchi, Stephanie Caroline Tavares ^[1] ; Kieliszek, Marek ^[2] ; Santos, Julio Cesar dos ^[1] ; da Silva, Silvio Silverio ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Engn Sch Lorena, BR-12602810 Lorena, SP - Brazil

^[2] Warsaw Univ Life Sci SGGW, Inst Food Sci, Dept Food Biotechnol & Microbiol, PL-02776 Warsaw - Poland

• Tipo de documento: Artigo Científico
• Fonte: METABOLITES; v. 10, n. 12 DEC 2020.
• Citações Web of Science: 0

Resumo

The production of biomolecules using agro-industrial by-products as feedstock is a growing trend worldwide. Selenium (Se) is a trace element essential for health, and the Se-enrichment of yeast biomass can enhance its benefits. This study investigated the feasibility of the production of Saccharomyces cerevisiae Se-enriched biomass using a medium composed of corn bran and soybean bran acid hydrolysates as carbon and nitrogen sources in a stirred-tank reactor. After hydrolysis, hydrolysates presented complex composition and high concentrations of sugars, proteins, and minerals. The use of a stirred-tank bioreactor leads to the production of 9 g/L S. cerevisiae biomass enriched with 236.93 mu g/g Se, and 99% cell viability. Likewise, the combination of sugarcane molasses and soybean bran hydrolysate was effective for cell growth of a probiotic strain of S. cerevisiae with a 24.08% beta-glucan content. The results demonstrated that starchy acid hydrolysates are low-cost and efficient substrates for the production of yeast biomass and derivate products and may contribute to further studies for a sustainable development of biorefinery technologies. (AU)

• Processo FAPESP: 16/10636-8 - Da fábrica celular à biorrefinaria integrada Biodiesel-Bioetanol: uma abordagem sistêmica aplicada a problemas complexos em micro e macroescalas
• Beneficiário: Roberto de Campos Giordano
• Modalidade de apoio: Auxílio à Pesquisa - Programa BIOEN - Temático