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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

A New Approach for the Production of Selenium-Enriched and Probiotic Yeast Biomass from Agro-Industrial by-Products in a Stirred-Tank Bioreactor

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Author(s):
Martiniano, Sabrina Evelin [1] ; Fernandes, Leticia Alves [1] ; Alba, Edith Mier [1] ; Philippini, Rafael Rodrigues [1] ; Tabuchi, Stephanie Caroline Tavares [1] ; Kieliszek, Marek [2] ; Santos, Julio Cesar dos [1] ; da Silva, Silvio Silverio [1]
Total Authors: 8
Affiliation:
[1] Univ Sao Paulo, Engn Sch Lorena, BR-12602810 Lorena, SP - Brazil
[2] Warsaw Univ Life Sci SGGW, Inst Food Sci, Dept Food Biotechnol & Microbiol, PL-02776 Warsaw - Poland
Total Affiliations: 2
Document type: Journal article
Source: METABOLITES; v. 10, n. 12 DEC 2020.
Web of Science Citations: 0
Abstract

The production of biomolecules using agro-industrial by-products as feedstock is a growing trend worldwide. Selenium (Se) is a trace element essential for health, and the Se-enrichment of yeast biomass can enhance its benefits. This study investigated the feasibility of the production of Saccharomyces cerevisiae Se-enriched biomass using a medium composed of corn bran and soybean bran acid hydrolysates as carbon and nitrogen sources in a stirred-tank reactor. After hydrolysis, hydrolysates presented complex composition and high concentrations of sugars, proteins, and minerals. The use of a stirred-tank bioreactor leads to the production of 9 g/L S. cerevisiae biomass enriched with 236.93 mu g/g Se, and 99% cell viability. Likewise, the combination of sugarcane molasses and soybean bran hydrolysate was effective for cell growth of a probiotic strain of S. cerevisiae with a 24.08% beta-glucan content. The results demonstrated that starchy acid hydrolysates are low-cost and efficient substrates for the production of yeast biomass and derivate products and may contribute to further studies for a sustainable development of biorefinery technologies. (AU)

FAPESP's process: 16/10636-8 - From the cell factory to the Biodiesel-Bioethanol integrated biorefinery: a systems approach applied to complex problems in micro and macroscales
Grantee:Roberto de Campos Giordano
Support Opportunities: Program for Research on Bioenergy (BIOEN) - Thematic Grants