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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

Current advances concerning the most cited metal ions doped bioceramics and silicate-based bioactive glasses for bone tissue engineering

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Autor(es):
Schatkoski, Vanessa Modelski [1] ; Montanheiro, Thais Larissa do Amaral [1] ; Canuto de Menezes, Beatriz Rossi [1] ; Pereira, Raissa Monteiro [1] ; Rodrigues, Karla Faquine [1] ; Ribas, Renata Guimaraes [1] ; da Silva, Diego Morais [1] ; Thim, Gilmar Patrocinio [1]
Número total de Autores: 8
Afiliação do(s) autor(es):
[1] Technol Inst Aeronaut ITA, Lab Plasmas & Proc LAB LPP, Praca Marechal Eduardo Gomes 50, BR-12228900 Sao Jose Dos Campos, SP - Brazil
Número total de Afiliações: 1
Tipo de documento: Artigo de Revisão
Fonte: CERAMICS INTERNATIONAL; v. 47, n. 3, p. 2999-3012, FEB 1 2021.
Citações Web of Science: 0
Resumo

Studies related to biomaterials that stimulate the repair of living tissue have increased considerably, improving the quality of many people's lives that require surgery due to traumatic accidents, bone diseases, bone defects, and reconstructions. Among these biomaterials, bioceramics and bioactive glasses (BGs) have proved to be suitable for coating materials, cement, scaffolds, and nanoparticles, once they present good biocompatibility and degradability, able to generate osteoconduction on the surrounding tissue. However, the role of biomaterials in hard tissue engineering is not restricted to a structural replacement or for guiding tissue regeneration. Nowadays, it is expected that biomaterials develop a multifunctional role when implanted, orchestrating the process of tissue regeneration and providing to the body the capacity to heal itself. In this way, the incorporation of specific metal ions in bioceramics and BGs structure, including magnesium, silver, strontium, lithium, copper, iron, zinc, cobalt, and manganese are currently receiving enhanced interest as biomaterials for biomedical applications. When an ion is incorporated into the bioceramic structure, a new category of material is created, which has several unique properties that overcome the disadvantages of primitive material and favors its use in different biomedical applications. The doping can enhance handling properties, angiogenic and osteogenic performance, and antimicrobial activity. Therefore, this review aims to summarize the effect of selected metal ion dopants into bioceramics and silicate-based BGs in bone tissue engineering. Furthermore, new applications for doped bioceramics and BGs are highlighted, including cancer treatment and drug delivery. (AU)

Processo FAPESP: 18/12035-7 - Propriedades mecânicas e antimicrobianas de nanocompósito Ag/PMMA
Beneficiário:Gilmar Patrocínio Thim
Linha de fomento: Auxílio à Pesquisa - Regular
Processo FAPESP: 17/02846-5 - Nanocompósito AgVO3/PMMA: Efeito da funcionalização com acrilamida nas propriedades mecânicas e antimicrobianas
Beneficiário:Beatriz Rossi Canuto de Menezes Rodrigues
Linha de fomento: Bolsas no Brasil - Doutorado
Processo FAPESP: 17/27079-7 - Reforço de um cimento de wollastonita (CaSiO3) por nanotubos de carbono para aplicações biomédicas ou odontológicas
Beneficiário:Renata Guimarães Ribas
Linha de fomento: Bolsas no Brasil - Doutorado
Processo FAPESP: 17/24873-4 - Nanocompósito de PHBV e NTC funcionalizado com hidroxibutirato: estudo cinético da cristalização e correlação com as propriedades mecânicas
Beneficiário:Thaís Larissa do Amaral Montanheiro
Linha de fomento: Bolsas no Brasil - Pós-Doutorado