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(Referência obtida automaticamente do Web of Science, por meio da informação sobre o financiamento pela FAPESP e o número do processo correspondente, incluída na publicação pelos autores.)

SiO2-Ag Composite as a Highly Virucidal Material: A Roadmap that Rapidly Eliminates SARS-CoV-2

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Autor(es):
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Assis, Marcelo [1, 2] ; Simoes, Luiz Gustavo P. [3] ; Tremiliosi, Guilherme C. [3] ; Coelho, Dyovani [2] ; Minozzi, Daniel T. [3] ; Santos, I, Renato ; Vilela, Daiane C. B. [4] ; do Santos, Jeziel Rodrigues [2] ; Ribeiro, Lara Kelly [2] ; Viana Rosa, Ieda Lucia [2] ; Mascaro, Lucia Helena [2] ; Andres, Juan [1] ; Longo, Elson [2]
Número total de Autores: 13
Afiliação do(s) autor(es):
[1] Univ Jaume I UJI, Dept Phys & Analyt Chem, Castellon de La Plana 12071 - Spain
[2] Fed Univ Sao Carlos UFSCar, LIEC, CDMF, BR-13565905 Sao Carlos, SP - Brazil
[3] Nanox Tecnol SA, BR-13562400 Sao Carlos, SP - Brazil
[4] Santos, Renato, I, Nanox Tecnol SA, BR-13562400 Sao Carlos, SP - Brazil
Número total de Afiliações: 4
Tipo de documento: Artigo Científico
Fonte: NANOMATERIALS; v. 11, n. 3 MAR 2021.
Citações Web of Science: 0
Resumo

COVID-19, as the cause of a global pandemic, has resulted in lockdowns all over the world since early 2020. Both theoretical and experimental efforts are being made to find an effective treatment to suppress the virus, constituting the forefront of current global safety concerns and a significant burden on global economies. The development of innovative materials able to prevent the transmission, spread, and entry of COVID-19 pathogens into the human body is currently in the spotlight. The synthesis of these materials is, therefore, gaining momentum, as methods providing nontoxic and environmentally friendly procedures are in high demand. Here, a highly virucidal material constructed from SiO2-Ag composite immobilized in a polymeric matrix (ethyl vinyl acetate) is presented. The experimental results indicated that the as-fabricated samples exhibited high antibacterial activity towards Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) as well as towards SARS-CoV-2. Based on the present results and radical scavenger experiments, we propose a possible mechanism to explain the enhancement of the biocidal activity. In the presence of O-2 and H2O, the plasmon-assisted surface mechanism is the major reaction channel generating reactive oxygen species (ROS). We believe that the present strategy based on the plasmonic effect would be a significant contribution to the design and preparation of efficient biocidal materials. This fundamental research is a precedent for the design and application of adequate technology to the next-generation of antiviral surfaces to combat SARS-CoV-2. (AU)

Processo FAPESP: 17/11986-5 - Geração e Armazenamento de Novas Energias: trazendo desenvolvimento tecnológico para o país
Beneficiário:Ana Flávia Nogueira
Modalidade de apoio: Auxílio à Pesquisa - Programa Centros de Pesquisa em Engenharia
Processo FAPESP: 13/07296-2 - CDMF - Centro de Desenvolvimento de Materiais Funcionais
Beneficiário:Elson Longo da Silva
Modalidade de apoio: Auxílio à Pesquisa - Centros de Pesquisa, Inovação e Difusão - CEPIDs
Processo FAPESP: 11/51084-4 - Escalonamento e implementação de controle de qualidade para produção de antimicrobianos nanoestruturados para aplicação em cerâmicas e plásticos
Beneficiário:Luiz Gustavo Pagotto Simões
Modalidade de apoio: Auxílio à Pesquisa - PAPPE / PIPE III