| Full text | |
| Author(s): Show less - |
Assis, Marcelo
[1, 2]
;
Simoes, Luiz Gustavo P.
[3]
;
Tremiliosi, Guilherme C.
[3]
;
Coelho, Dyovani
[2]
;
Minozzi, Daniel T.
[3]
;
Santos, I, Renato
;
Vilela, Daiane C. B.
[4]
;
do Santos, Jeziel Rodrigues
[2]
;
Ribeiro, Lara Kelly
[2]
;
Viana Rosa, Ieda Lucia
[2]
;
Mascaro, Lucia Helena
[2]
;
Andres, Juan
[1]
;
Longo, Elson
[2]
Total Authors: 13
|
| Affiliation: | [1] Univ Jaume I UJI, Dept Phys & Analyt Chem, Castellon de La Plana 12071 - Spain
[2] Fed Univ Sao Carlos UFSCar, LIEC, CDMF, BR-13565905 Sao Carlos, SP - Brazil
[3] Nanox Tecnol SA, BR-13562400 Sao Carlos, SP - Brazil
[4] Santos, Renato, I, Nanox Tecnol SA, BR-13562400 Sao Carlos, SP - Brazil
Total Affiliations: 4
|
| Document type: | Journal article |
| Source: | NANOMATERIALS; v. 11, n. 3 MAR 2021. |
| Web of Science Citations: | 0 |
| Abstract | |
COVID-19, as the cause of a global pandemic, has resulted in lockdowns all over the world since early 2020. Both theoretical and experimental efforts are being made to find an effective treatment to suppress the virus, constituting the forefront of current global safety concerns and a significant burden on global economies. The development of innovative materials able to prevent the transmission, spread, and entry of COVID-19 pathogens into the human body is currently in the spotlight. The synthesis of these materials is, therefore, gaining momentum, as methods providing nontoxic and environmentally friendly procedures are in high demand. Here, a highly virucidal material constructed from SiO2-Ag composite immobilized in a polymeric matrix (ethyl vinyl acetate) is presented. The experimental results indicated that the as-fabricated samples exhibited high antibacterial activity towards Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) as well as towards SARS-CoV-2. Based on the present results and radical scavenger experiments, we propose a possible mechanism to explain the enhancement of the biocidal activity. In the presence of O-2 and H2O, the plasmon-assisted surface mechanism is the major reaction channel generating reactive oxygen species (ROS). We believe that the present strategy based on the plasmonic effect would be a significant contribution to the design and preparation of efficient biocidal materials. This fundamental research is a precedent for the design and application of adequate technology to the next-generation of antiviral surfaces to combat SARS-CoV-2. (AU) | |
| FAPESP's process: | 17/11986-5 - Generation and storage of New Energy: bringing technological development for the country |
| Grantee: | Ana Flávia Nogueira |
| Support Opportunities: | Research Grants - Research Centers in Engineering Program |
| FAPESP's process: | 13/07296-2 - CDMF - Center for the Development of Functional Materials |
| Grantee: | Elson Longo da Silva |
| Support Opportunities: | Research Grants - Research, Innovation and Dissemination Centers - RIDC |
| FAPESP's process: | 11/51084-4 - Scaling and implementing quality control for the production of nanostructured antimicrobials for use in ceramics and plastics |
| Grantee: | Luiz Gustavo Pagotto Simões |
| Support Opportunities: | Research Grants - Program to Support Research in Small Business (PAPPE / PIPE III) |