The Mechanoreceptor's Role in Plantar Skin Changes in Individuals with Diabetes Mellitus

Autor(es)

Zippenfennig, Claudio ^[1] ; Drechsel, Tina J. ^[1] ; Monteiro, Renan L. ^[2] ; Sacco, Isabel C. N. ^[2] ; Milani, Thomas L. ^[1]

Afiliação do(s) autor(es)

^[1] Tech Univ Chemnitz, Fac Behav & Social Sci, Inst Human Movement Sci & Hlth, Dept Human Locomot, D-09107 Chemnitz - Germany

^[2] Univ Sao Paulo, Fac Med, Dept Phys Therapy Speech & Occupat Therapy, BR-05360160 Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF CLINICAL MEDICINE; v. 10, n. 12 JUN 2021.
• Citações Web of Science: 0

Resumo

Mechanical skin properties (MSPs) and vibration perception thresholds (VPTs) show no relationship in healthy subjects. Similar results were expected when comparing MSP and VPT in individuals with diabetes mellitus (DM) and with diabetic (peripheral-)neuropathy (DPN). A healthy control group (33 CG), 20 DM and 13 DPN participated in this cross-sectional study. DM and DPN were classified by using a fuzzy decision support system. VPTs (in mu m) were measured with a modified vibration exciter at two different frequencies (30 and 200 Hz) and locations (heel, first metatarsal head). Skin hardness (durometer readings) and thickness (ultrasound) were measured at the same locations. DPN showed the highest VPTs compared to DM and CG at both frequencies and locations. Skin was harder in DPN compared to CG (heel). No differences were observed in skin thickness. VPTs at 30 and 200 Hz correlated negatively with skin hardness for DPN and with skin thickness for DM, respectively. This means, the harder or thicker the skin, the better the perception of 30 or 200 Hz vibrations. Changes in MSP may compensate the loss of sensitivity up to a certain progression of the disease. However, the influence seems rather small when considering other parameters, such as age. (AU)

• Processo FAPESP: 17/17848-3 - Efeitos do fortalecimento dos músculos dos pés na atividade física de vida diária e funcionalidade de tornozelo e pé de pessoas com polineuropatia diabética: um ensaio clínico controlado randomizado
• Beneficiário: Renan Lima Monteiro
• Modalidade de apoio: Bolsas no Brasil - Doutorado