| Texto completo | |
| Autor(es): |
Kiraly, Peter
[1, 2]
;
Dal Poggetto, Guilherme
[3, 1]
;
Castanar, Laura
[1]
;
Nilsson, Mathias
[1]
;
Deak, Andrea
[4]
;
Morris, Gareth A.
[1]
Número total de Autores: 6
|
| Afiliação do(s) autor(es): | [1] Univ Manchester, Dept Chem, Oxford Rd, Manchester M13 9PL, Lancs - England
[2] JEOL UK Ltd, Long Hanborough OX29 8SP - England
[3] Univ Campinas UNICAMP, Inst Chem, POB 6154, BR-13083970 Campinas, SP - Brazil
[4] Inst Mat & Environm Chem, Res Ctr Nat Sci, Supramol Chem Res Grp, Eotvos Lorand Res Network ELKH, Magyar Tudosok Korutja 2, H-1117 Budapest - Hungary
Número total de Afiliações: 4
|
| Tipo de documento: | Artigo Científico |
| Fonte: | CHEMICAL SCIENCE; v. 12, n. 34 AUG 2021. |
| Citações Web of Science: | 0 |
| Resumo | |
Accurate measurement of transverse relaxation rates in coupled spin systems is important in the study of molecular dynamics, but is severely complicated by the signal modulations caused by scalar couplings in spin echo experiments. The most widely used experiments for measuring transverse relaxation in coupled systems, CPMG and PROJECT, can suppress such modulations, but they also both suppress some relaxation contributions, and average relaxation rates between coupled spins. Here we introduce a new experiment which for the first time allows accurate broadband measurement of transverse relaxation rates of coupled protons, and hence the determination of exchange rate constants in slow exchange from relaxation measurements. The problems encountered with existing methods are illustrated, and the use of the new method is demonstrated for the classic case of hindered amide rotation and for the more challenging problem of exchange between helical enantiomers of a gold(i) complex. (AU) | |
| Processo FAPESP: | 18/19253-0 - Novas sequências de pulso e ferramentas de processamento para experimentos multidimensionais em RMN: Aplicação em análises de misturas de produtos naturais |
| Beneficiário: | Guilherme Fonseca Dal Poggetto |
| Modalidade de apoio: | Bolsas no Brasil - Pós-Doutorado |