Interleukin-15 and creatine kinase response to high-intensity intermittent exercise training

Autor(es)

dos Santos, Thaislaine ^[1] ; Lira, Fabio Santos ^[1] ; Antunes, Barbara Moura ^[1]

Afiliação do(s) autor(es)

^[1] Sao Paulo State Univ Unesp, Sch Technol & Sci, Dept Phys Educ, Exercise & Immunometab Res Grp, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: SPORT SCIENCES FOR HEALTH; v. 16, n. 3, p. 479-484, SEP 2020.
• Citações Web of Science: 0

Resumo

PurposeTo verify the acute and chronic effects of high-intensity intermittent training (HIIT) on interleukin 15 (IL-15) response and the relationship between circulating IL-15 concentrations and muscle damage in young men.MethodsPhysically active men performed two different training protocols at moderate and high intensity, three times per week for 5 weeks. Twenty subjects were randomly allocated into high-intensity intermittent training group (HIIT-5 km 1 min at 100% of maximal aerobic speed interspersed by 1 min passive recovery; n=10) or moderate-intensity continuous training group (MICT-5 km 70% of maximal aerobic speed; n=10). An acute exercise session was performed with blood sample collection pre-exercise, immediately post-exercise, and 60 min post-exercise (before and after 5 weeks of training). Blood samples were used to analyze serum IL-15 and creatine kinase (CK) concentrations.ResultsThe results showed no changes in serum IL-15 concentrations independent of protocol, moment measurement, and intervention period. CK concentrations showed higher values post-exercise when compared to pre-exercise in both protocols. No significant relationship was found between serum IL-15 and CK concentrations.ConclusionOur findings point to the absence of acute and chronic changes in serum IL-15 concentrations in response to 5 weeks of high-intensity intermittent training. In addition, data suggest that the release of this cytokine is not related to muscle damage in healthy young men. (AU)

• Processo FAPESP: 16/12145-1 - Treinamento intermitente de alta intensidade e resposta anti-inflamatória sistêmica
• Beneficiário: Thaislaine dos Santos
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica