Nebulized plasma-activated water has an effective antimicrobial effect on medically relevant microbial species and maintains its physicochemical properties in tube lengths from 0.1 up to 1.0 m

Autor(es)

Chiappim, William ^{[1, 2]} ; Sampaio, Aline ^[3] ; Miranda, Felipe ^[1] ; Petraconi, Gilberto ^[1] ; da Silva Sobrinho, Argemiro ^[1] ; Cardoso, Paulo ^[4] ; Kostov, Konstantin ^[5] ; Koga-Ito, Cristiane ^[3] ; Pessoa, Rodrigo ^[1]

Afiliação do(s) autor(es)

^[1] Inst Tecnol Aeronaut ITA, Lab Plasmas & Proc, BR-12228900 Sao Jose Dos Campos - Brazil

^[2] Univ Aveiro, i3N, Dept Fis, Campus Santiago, Aveiro - Portugal

^[3] UNESP, Inst Ciencia & Tecnol ICT, Lab Genoma, Sao Jose Dos Campos - Brazil

^[4] Univ Sao Paulo, Hosp Clin HCFMUSP, Inst Coracao, Div Thorac Surg, Fac Med, Sao Paulo - Brazil

^[5] UNESP, Fac Engn FEG, Pedregulho - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Plasma Processes and Polymers; v. 18, n. 11 AUG 2021.
• Citações Web of Science: 1

Resumo

This study applies a proof of concept for future applications in controlling the microbiota in tubes and tracheal appliances used in the respiratory tract. Therefore, the physical-chemical parameters of the plasma-activated and nebulized water (NPAW) are measured in a nebulizer tube with different lengths between 0.1 and 3.0 m. The pH values and oxidation-reduction potential (ORP) do not change during nebulization of PAW over a 1.0 m tube. However, for longer lengths, there is an increase in pH and a decrease in ORP. At 3.0 m, the pH increases approximately 16% compared with the 1.0 m position with a 20% decrease in the ORP values. Hydrogen peroxide (H2O2) measured quantitatively using test strips presents values between 0.5 and 2.0 mg/L for condensed NPAW in different tube lengths between 0.1 and 3.0 m, and maintains the approximate value of 2.0 mg/L in tubes up to 1.0 m, with a reduction proportional to the increase in the length of the tube. The antimicrobial efficacy of NPAW applied for 15 min shows the inactivation of Staphylococcus aureus and Escherichia coli but without significant inactivation of Candida albicans. (AU)

• Processo FAPESP: 19/25652-7 - Aplicação do plasma de baixa temperatura sob pressão atmosférica como adjuvante ao tratamento da Mucosite Oral
• Beneficiário: Aline da Graça Sampaio
• Modalidade de apoio: Bolsas no Brasil - Doutorado
• Processo FAPESP: 19/05856-7 - Aplicações de plasmas atmosféricos não-térmicos na odontologia: da bancada para a clínica
• Beneficiário: Cristiane Yumi Koga Ito
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Processo FAPESP: 20/10450-7 - Explorando o potencial do líquido ativado com plasma (PAL): caracterização do plasma e aplicação do PAL no tratamento endodôntico
• Beneficiário: William Chiappim Junior
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado