Current status of research regarding Blastocystis sp., an enigmatic protist, in Brazil

Autor(es)

de Melo, Gessica Baptista ^{[1, 2]} ; Bosqui, Larissa Rodrigues ^[3] ; da Costa, Idessania Nazareth ^[3] ; de Paula, Fabiana Martins ^{[1, 2]} ; Borges Gryschek, Ronaldo Cesar ^{[1, 2]}

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Hosp Clin HCFMUSP, Fac Med, Lab Invest Med LIM06, Lab Imunopatol Esquistossome, Sao Paulo, SP - Brazil

^[2] Univ Sao Paulo, Fac Med FMUSP, Inst Med Trop IMT, Secao Helmintol, Sao Paulo, SP - Brazil

^[3] Univ Estadual Londrina UEL, Lab Imunoparasitol Doencas Negligenciadas & Canc, Londrina, Parana - Brazil

• Tipo de documento: Artigo Científico
• Fonte: Clinics; v. 76, 2021.
• Citações Web of Science: 0

Resumo

The present study aimed to evaluate the occurrence of Blastocystis sp. in Brazilian studies over a period of years (2000-2020), as well as point out relevant aspects of this enigmatic organism. We performed a literature search using six sources of international databases. The data were divided into diagnostic by parasitological and molecular techniques, and relevant aspects. After applying the inclusion and exclusion criteria, 52 studies were included in the final analysis. The occurrence of Blastocystis sp. in Brazil ranged from 0.5% to 86.6%, as determined using parasitological techniques. The highest occurrence was in the North (27.3%) and the lowest, in the Midwest region (13.4%). In Brazil, most studies have employed molecular techniques and are concentrated in the Southeast region. The Blastocystis sp. subtype ST3 had the highest average positivity, followed by ST1 and ST2. These findings represent a panorama that reflects the reality of Brazil; thus, we believe that the effectiveness of parasitological diagnosis should be considered with regard to making an appropriate choice of technique for detecting Blastocystis sp. Additionally, we emphasize the importance of further studies in the context of molecular epidemiology with regard to this genus. Blastocystis sp. is not well understood yet, and very little information regarding this genus is available; hence, further research regarding this genus is urgently needed. (AU)

• Processo FAPESP: 15/18213-6 - Identificação de genótipos de Blastocystis spp. em amostras de fezes e sua relação com urticária crônica
• Beneficiário: Ronaldo Cesar Borges Cryschek
• Modalidade de apoio: Auxílio à Pesquisa - Regular