Photochemical and photophysical properties of tetracarboxylic acid phthalocyanines from glycolic and lactic acids in homogeneous and micro heterogeneous media

Autor(es)

Silva, Charles Biral ^[1] ; Antonio, Felipe Cesar Torres ^[1] ; Homem-de-Mello, Paula ^[1] ; Ribeiro, Anderson Orzari ^[1] ; do Nascimento, Francisco Batista ^[1] ; de Oliveira, Hueder Paulo Moises ^[1]

Afiliação do(s) autor(es)

^[1] Fed Univ ABC, Ctr Nat & Human Sci, Ave Estados 5001, BR-09210580 Santo Andre, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY; v. 263, DEC 15 2021.
• Citações Web of Science: 0

Resumo

Glycolic acid and lactic acid substituted zinc phthalocyanines were studied concerning their photophysical and photochemical properties in eight organic solvents (homogeneous medium) and in aqueous media with the presence of CTAB and PVP 360 surfactants. Solvent effects were investigated according to several physical solvent parameters, including studies that used more than one parameter at a time, such as the E-T(30) scale and the Lippet-Mataga equation. Computational studies were realized and was found in good agreement with experimental data indicating J-type dimers' formation through hydrogen bonds, which may not affect the spectroscopic properties. Fluorescence lifetimes were recorded using a time-correlated single-photon counting setup (TCSPC) technique. The direct method (analyzing the phosphorescence decay curves of singlet oxygen at 1270 nm) was employed to study singlet oxygen quantum yields. Phthalocyanine macrocycle with lactic acid substituent showed better solvation arrangement than the glycolic derivative, which can be explained based on the presence of the methyl group bonded to the chain. The water solvation of Pc's in the presence of cationic surfactant (CTAB) and biocompatible polymer PVP 360 increses the importance of this study for appliance in photodynamic therapy (PDT). (C) 2021 Elsevier B.V. All rights reserved. (AU)

• Processo FAPESP: 17/21199-0 - As variedades diferenciáveis da teoria da estrutura eletrônica
• Beneficiário: Yuri Alexandre Aoto
• Modalidade de apoio: Auxílio à Pesquisa - Jovens Pesquisadores
• Processo FAPESP: 14/18527-8 - Ftalocianinas e Naftalocianinas: síntese de macrociclos anfifílicos para aplicação em Terapia Fotodinâmica
• Beneficiário: Anderson Orzari Ribeiro
• Modalidade de apoio: Auxílio à Pesquisa - Regular