Tick-borne zoonotic agents infecting horses from an urban area in Midwestern Brazil: epidemiological and hematological features

Autor(es):Mostrar menos -

Campos, Joao Bosco Vilela ^[1] ; Martins, Filipe Santos ^[1] ; de Oliveira, Carina Elisei ^[1] ; Taveira, Amanda Alves ^[1] ; Oliveira, Joao Roberto de ^[1] ; Goncalves, Luiz Ricardo ^[2] ; Cordeiro, Matheus Dias ^[3] ; Calchi, Ana Claudia ^[2] ; de Campos Binder, Lina ^[4] ; Serpa, Maria Carolina de Azevedo ^[4] ; Barbieri, Amalia Regina Mar ^[4] ; Labruna, Marcelo B. ^[4] ; Machado, Rosangela Zacarias ^[2] ; de Andrade, Gisele Braziliano ^[1] ; Andre, Marcos Rogerio ^[2] ; Herrera, Heitor Miraglia ^[1]

Afiliação do(s) autor(es)

^[1] Univ Catolica Dom Bosco, Dept Biosaude, Lab Insana Huna Interface Anim Environm & Human H, Campo Grande, MS - Brazil

^[2] Univ Estadual Paulista, Dept Pathol, Immunoparasitol Lab, Campus Jaboticabal, Jaboticabal, SP - Brazil

^[3] Univ Fed Rural Rio De Janeiro, Lab Parasit Dis, Rio De Janeiro - Brazil

^[4] Univ Sao Paulo, Dept Prevent Vet Med & Anim Hlth, Sao Paulo - Brazil

• Tipo de documento: Artigo Científico
• Fonte: TROPICAL ANIMAL HEALTH AND PRODUCTION; v. 53, n. 5 NOV 2021.
• Citações Web of Science: 0

Resumo

The emergence of tick-borne diseases has been reported as a serious problem in public health worldwide and many aspects of its epidemiology and effects on the health of its hosts are unclear. We aimed to perform an epidemiological study of tick-borne zoonotic Rickettsia, Borrelia, and Anaplasmataceae in horses from Midwestern Brazil. We also evaluated whether Borrelia spp. and Anaplasmataceae may be associated with hematological disorders in the sampled animals. Blood and serum samples as well as ticks were collected from 262 horses. Serum samples were used to perform serological tests, and hematological analyses were made using whole blood. Furthermore, DNA extracted from whole blood and ticks was used for molecular tests. Campo Grande is enzootic for tick-borne studied bacteria, since we found an overall exposure of 59.9% of the sampled horses, 28.7% of them presented co-exposure. Seropositivity rates of 20.6% for Borrelia spp., 25.6% for Rickettsia spp., and 31.6% for Anaplasmataceae were found in the sampled horses. Considering both molecular and serological tests for Borrelia spp., the infection rate was 48.0% (126/262). None of the tested horses showed molecular positivity for Anaplasma phagocytophilum. The horses sampled displayed 7.2% of parasitism by ixodid ticks in single and coinfestations. We did not find DNA of any studied bacteria in the sampled ticks. Positive horses for Borrelia spp. and Anaplasmataceae agents displayed leukopenia, monocytopenia, and lymphopenia. Together, our results suggest that horses may play a role as sentinel host for zoonotic bacteria and Borrelia spp. and Anaplasmataceae agents can impair the health of horses. (AU)

• Processo FAPESP: 18/02753-0 - ISOLAMENTO E GENOTIPAGEM DE Bartonella spp. EM MAMIFEROS RESERVATÓRIOS DOMÉSTICOS E SELVAGENS NO BRASIL
• Beneficiário: Marcos Rogério André
• Modalidade de apoio: Auxílio à Pesquisa - Regular