Recombination mapping of the Brazilian stingless bee Frieseomelitta varia confirms high recombination rates in social hymenoptera

Autor(es)

Waiker, Prashant ^[1] ; Pinto de Abreu, Fabiano Carlos ^[2] ; Luna-Lucena, Danielle ^[3] ; Paula Freitas, Flavia Cristina ^{[3, 4]} ; Paulino Simoes, Zila Luz ^[2] ; Rueppell, Olav ^{[5, 1]}

Afiliação do(s) autor(es)

^[1] Univ North Carolina Greensboro, Biol Dept, 321 McIver St, Greensboro, NC 27412 - USA

^[2] Univ Sao Paulo, Fac Filosofia Ciencias & Letras Ribeirao Preto, Dept Biol, Ribeirao Preto, SP - Brazil

^[3] Univ Sao Paulo, Dept Genet, Fac Med Ribeirao Preto, Ribeirao Preto, SP - Brazil

^[4] Univ Fed Alfenas, Inst Ciencias Biomed, Dept Biol Celular & Desenvolvimento, Alfenas, MG - Brazil

^[5] Univ Alberta, Dept Biol Sci, Edmonton, AB T6G 2E9 - Canada

• Tipo de documento: Artigo Científico
• Fonte: BMC Genomics; v. 22, n. 1 SEP 18 2021.
• Citações Web of Science: 0

Resumo

Background Meiotic recombination is a fundamental genetic process that shuffles allele combinations and promotes accurate segregation of chromosomes. Analyses of the ubiquitous variation of recombination rates within and across species suggest that recombination is evolving adaptively. All studied insects with advanced eusociality have shown exceptionally high recombination rates, which may represent a prominent case of adaptive evolution of recombination. However, our understanding of the relationship between social evolution and recombination rates is incomplete, partly due to lacking empirical data. Here, we present a linkage map of the monandrous, advanced eusocial Brazilian stingless bee, Frieseomelitta varia, providing the first recombination analysis in the diverse Meliponini (Hymenoptera, Apidae). Results Our linkage map includes 1417 markers in 19 linkage groups. This map spans approximately 2580 centimorgans, and comparisons to the physical genome assembly indicate that it covers more than 75 % of the 275 Megabasepairs (Mbp) F. varia genome. Thus, our study results in a genome-wide recombination rate estimate of 9.3-12.5 centimorgan per Mbp. This value is higher than estimates from nonsocial insects and comparable to other highly social species, although it does not support our prediction that monandry and strong queen-worker caste divergence of F. varia lead to even higher recombination rates than other advanced eusocial species. Conclusions Our study expands the association between elevated recombination and sociality in the order Hymenoptera and strengthens the support for the hypothesis that advanced social evolution in hymenopteran insects invariably selects for high genomic recombination rates. (AU)

• Processo FAPESP: 16/06657-0 - Análise do sistema endócrino e do ciclo circadiano como moduladores do desenvolvimento de Apis mellifera
• Beneficiário: Zilá Luz Paulino Simões
• Modalidade de apoio: Auxílio à Pesquisa - Regular