Physical, functional and biochemical features of Nanoskin (R) bacterial cellulose scaffold as a potential carrier for cell transference

Autor(es)

Hata Viveiros, Magda Massae ^[1] ; Rainho, Claudia Aparecida ^[1] ; Zamame Ramirez, Jofer Andree ^[1] ; Kaneno, Ramon ^[1] ; Silva, Marcia Guimaraes ^[1] ; Ximenes, Valdecir Farias ^[1] ; de Olyveira, Gabriel Molina ^[2] ; Basmaji, Pierre ^[2] ; Di Girolamo, Nick ^[3] ; Schellini, Silvana Artioli ^[1]

Afiliação do(s) autor(es)

^[1] State Univ Sao Paulo UNESP, Sao Paulo, SP - Brazil

^[2] Innovatecs Biotechnol Res & Dev, Sao Carlos, SP - Brazil

^[3] Univ New South Wales, Sch Med Sci, Sydney, NSW - Australia

• Tipo de documento: Artigo Científico
• Fonte: Materials Letters; v. 308, n. A FEB 1 2022.
• Citações Web of Science: 0

Resumo

We evaluated the feasibility of Nanoskin (R), a bacterial cellulose (BC) nanofiber membrane, as a potential scaffold for cell transference therapy. Nanoskin (R) does not induce lymphocyte proliferation, but it does not kill lymphocytes. Human mesenchymal stem cells (MSCs) and lymphocytes produced significantly elevated amounts of interleukin (IL)-10 (p = 0.0005; p = 0.02) when in contact with Nanoskin (R). In conclusion, the Nanoskin (R) can be a promising biomaterial for use as a cell carrier-scaffold in cell transference therapies. (AU)

• Processo FAPESP: 15/10727-0 - Cultivo de células tronco mesenquimais de medula óssea humana sobre scaffolds de Nanoskin para a reconstrução da superfície ocular.
• Beneficiário: Silvana Artioli Schellini
• Modalidade de apoio: Auxílio à Pesquisa - Regular