iomineralization induced by chitosan and collagen-based materials with fluoride for dentin coverage: Chemical and morphological analysi

Autor(es)

Nahorny, Sidnei ^{[1, 2]} ; de Oliveira, Ivone Regina ^[2] ; Silva Soares, Luis Eduardo ^[1]

Afiliação do(s) autor(es)

^[1] Univ Vale Paraiba, Inst Pesquisa & Desenvolvimento IP8D, Lab Odontol & Mat Aplicados, Av Shishima Hifumi, Sao Jose Dos Campos, SP - Brazil

^[2] Univ Vale Paraiba, Inst Pesquisa & Desenvolvimento IP8D, Lab Ceram Avancadas, Av Shishima Hifumi, Sao Jose Dos Campos, SP - Brazil

• Tipo de documento: Artigo Científico
• Fonte: MICROSCOPY RESEARCH AND TECHNIQUE; v. 85, n. 3 NOV 2021.
• Citações Web of Science: 0

Resumo

The prevention and treatment of erosive tooth wear are becoming increasingly important due to its increasing prevalence. The use of natural solutions to modify dental surfaces has become an area of research. Organic materials such as chitosan and hydrolyzed collagen may be a promising option to treat dentin. This in vitro study aimed to evaluate the influence of chitosan or hydrolyzed collagen, alone or combined with acidulated phosphate fluoride (APF) gel, on the composition and morphology of dentin after erosion. Bovine dentin samples were prepared (n = 84) and treated with artificial saliva (AS, negative control); APF gel (F, positive control); chitosan solution (Chi); hydrolyzed collagen solution (Col); fluoride/chitosan composition (F\_Chi); and fluoride/hydrolyzed collagen composition (F\_Col). Erosive cycles (six cycles of immersion in orange juice for 1 min, followed by immersion in AS for 1 hr) were performed. The materials were characterized by their morphology, composition, and particle size distribution. Micro-energy dispersive X-ray fluorescence spectroscopy and scanning electron were used to evaluate the dentin's inorganic chemical composition and morphology. The F\_Col and F groups had a reduction in calcium loss by 17 and 26%, respectively (p < .001). Both of these groups still had a covering layer of agglomerates at the dentin surface after the erosive cycles. The fluoridated chitosan or collagen solutions improved the dentin resistance to erosion as a novel hybrid-fluoride-based material approach to provide surface protection from erosion. (AU)

• Processo FAPESP: 05/50811-9 - Estudo do colágeno da dentina por técnicas de microanálise
• Beneficiário: Airton Abrahao Martin
• Modalidade de apoio: Auxílio à Pesquisa - Regular