ighly divergent herpesviruses in threatened river dolphins from Brazi

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Novoselecki, Helena Exposto ^[1] ; Catao-Dias, Jose Luiz ^[1] ; Ewbank, Ana Carolina ^[1] ; Navas-Suarez, Pedro Enrique ^[1] ; Duarte-Benvenuto, Aricia ^[1] ; Lial, Henrique Christino ^[1] ; Silva, Samira Costa ^[1] ; Sanchez-Sarmiento, Angelica Maria ^[1] ; Gravena, Waleska ^{[2, 3]} ; Ferreira da Silva, Vera Maria ^[2] ; Carvalho, Vitor L. ^[4] ; Marmontel, Miriam ^[5] ; Bertozzi, Carolina P. ^[6] ; Ribeiro, Vanessa Lanes ^{[6, 7]} ; do Valle, Rodrigo del Rio ^[7] ; Marigo, Juliana ^[1] ; das Neves, Carlos G. ^[8] ; Esperon, Fernando ^[9] ; Sacristan, Carlos ^[1]

Afiliação do(s) autor(es)

^[1] Univ Sao Paulo, Sch Vet Med & Anim Sci, Dept Pathol, Lab Wildlife Comparat Pathol, BR-05508270 Sao Paulo, SP - Brazil

^[2] Inst Nacl de Pesquisas da Amazonia, BR-69067375 Manaus, Amazonas - Brazil

^[3] Univ Fed Amazonas, Inst Saude & Biotecnol, BR-69460000 Coari, AM - Brazil

^[4] Assoc Pesquisa & Preservacao Ecossistemas Aquat, BR-61627210 Caucaia, CE - Brazil

^[5] Inst Desenvolvimento Sustentavel Mamiraua, BR-69553225 Tefe, AM - Brazil

^[6] Univ Estadual Paulista, UNESP, Inst Biociencias, Campus Litoral Paulista, Sao Vicente, SP - Brazil

^[7] Inst Biopesca, Praia Grande, SP - Brazil

^[8] Norwegian Vet Inst, Arboretveien 57, N-1433 As - Norway

^[9] Univ Europea Madrid, Sch Biomed & Hlth Sci, Vet Dept, C Tajo S-N, Madrid 28670 - Spain

• Tipo de documento: Artigo Científico
• Fonte: SCIENTIFIC REPORTS; v. 11, n. 1 DEC 31 2021.
• Citações Web of Science: 0

Resumo

River dolphins are a highly threatened polyphyletic group comprised of four odontocete families: Iniidae, Pontoporiidae, Lipotidae, and Platanistidae, the first two endemic to South America. To address the knowledge gap regarding infectious agents in this cetacean group, we surveyed the presence of herpesviruses by PCR in skin and/or blood samples of live-captured Amazon (Inia geoffrensis, n = 25) and Bolivian (Inia boliviensis, n = 22) river dolphins of the Amazon basin and in selected tissue samples of franciscanas (Pontoporia blainvillei, n = 27) stranded or bycaught in southeastern Brazil. Additionally, available franciscana tissue samples were examined by histopathology. Herpesvirus DNA was amplified in 13 Bolivian river dolphins (59.1%, 95% CI 38.5-79.6%) and 14 franciscanas (51.9%, 95% CI 33.0-70.7%). All Amazon river dolphins were herpesvirus-negative. Two different herpesviruses were found in Bolivian river dolphins: a previously known gammaherpesvirus detected in blood and/or skin samples of all positive individuals and a novel alphaherpesvirus in the skin of one animal. A new gammaherpesvirus was found in several franciscana samples-the first herpesvirus recorded in Pontoporiidae. Intranuclear inclusion bodies consistent with herpesvirus were observed in the lymph node of one franciscana. The high divergence among the obtained herpesviruses and those previously described can be explained by viral-host coevolution, and by the fact that these populations are fairly isolated. (AU)

• Processo FAPESP: 16/20956-0 - Identificação e quantificação dos genes de resistência a antimicrobianos no microbioma de aves marinhas do litoral Sul-Sudeste do Brasil
• Beneficiário: Ana Carolina Ewbank
• Modalidade de apoio: Bolsas no Brasil - Doutorado
• Processo FAPESP: 18/25069-7 - Estudo e caracterização de agentes virais emergentes selecionados e potencialmente associados a hepatopatias em cetáceos costeiros, pelágicos e de habitat misto no Brasil
• Beneficiário: Carlos Sacristan Yague
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado