iomonitoring of Exposure to Metals in a Population Residing in an Industrial Area in Brazil: A Feasibility Stud

Autor(es)

Campos, Elida ^[1] ; Freire, Carmen ^{[1, 2, 3]} ; Barbosa, Fernando ^[4] ; Lemos, Cristina ^[5] ; Saraceni, Valeria ^[5] ; Koifman, Rosalina J. ^[1] ; Pinheiro, Rafael do Nascimento ^[5] ; da Silva, Ilce Ferreira ^[1]

Afiliação do(s) autor(es)

^[1] Oswaldo Cruz Fdn FIOCRUZ, Dept Epidemiol & Quantitat Methods Hlth, Natl Sch Publ Hlth, BR-21040900 Rio De Janeiro - Brazil

^[2] Inst Invest Biosanit Granada ibs GRANADA, Granada 18012 - Spain

^[3] CIBER Epidemiol & Salud Publ CIBERESP, Madrid 28029 - Spain

^[4] Univ Sao Paulo, Sch Pharmaceut Sci Ribeirao Preto, BR-05508060 Sao Paulo - Brazil

^[5] Municipal Hlth Secretariat Rio De Janeiro, Superintendence Hlth Surveillance, BR-20211901 Rio De Janeiro - Brazil

• Tipo de documento: Artigo Científico
• Fonte: NTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALT; v. 18, n. 23 DEC 2021.
• Citações Web of Science: 0

Resumo

Background: Industries are sources of environmental pollutants. However, there are few human biomonitoring (HBM) studies in the vicinity of industrial areas. Thus, we evaluate the feasibility of conducting an HBM study to assess exposure to metals in an industrial area in Rio de Janeiro, Brazil. Methodology: A cross-sectional survey was conducted near a steel factory. Adults (exposed = 775; controls = 775) were randomly selected and sex-matched. Subjects were interviewed using a questionnaire and a 24 h dietary recall. Blood samples were collected to analyze metal concentrations, blood count, biochemical parameters, and thyroid hormones. The feasibility of the survey was assessed following guidelines. The descriptive analysis was performed for the first 250 participants (pilot study). Results: Adjustments were made to the survey execution, including age-matching, fieldwork team, questionnaire, blood collection, and research awareness. The complete questionnaire was answered by >= 97% of participants; metals were measured in >= 98% and clinical parameters in >= 89%, except thyroid hormones (13-44%). The average age and family income were of 50 years and USD 575/month, respectively. The participants had equal distribution among sexes: 50% had a medium education level, and 59% were nonwhite. Conclusion: This preliminary HBM study demonstrates feasibility for the total population, with results indicating representativeness of the target population. (AU)

• Processo FAPESP: 18/24069-3 - Do biomonitoramento ao reconhecimento de assinaturas do exposoma humano visando antecipar riscos para uma saúde contínua
• Beneficiário: Fernando Barbosa Júnior
• Modalidade de apoio: Auxílio à Pesquisa - Temático