| Texto completo | |
| Autor(es): |
Cemin, Felipe
;
Artico, Leonardo Luis
;
Piroli, Vanessa
;
Yunes, Jose Andres
;
Figueroa, Carlos Alejandro
;
Alvarez, Fernando
Número total de Autores: 6
|
| Tipo de documento: | Artigo Científico |
| Fonte: | Applied Surface Science; v. 596, p. 11-pg., 2022-09-15. |
| Resumo | |
This study combines the brand new concept of high-entropy designed materials with the superior properties of metallic glasses to obtain a NbTaTiVZr high-entropy metallic glass (HEMG) coating for biomedical applications. The amorphous structure is achieved by a room temperature magnetron sputtering deposition, whereas a bcc crystalline phase, typical of high-entropy alloys (HEA), is obtained at 400 degrees C. X-ray photoelectron spectroscopy showed that the oxygen concentration on the coatings surface is > 50% and significantly higher than in the bulk (similar to 5%). The NbTaTiVZr(O) HEMG surface is completely passivated, in contrast to the metallic + oxide outermost layer found for the HEA. Potentiodynamic polarization tests attested an improved corrosion resistance of the HEMG surface, which showed also increased hydrophilicity compared to the crystalline sample. In vitro biocompatibility investigations using both the hTERT-immortalized bone marrow mesenchymal cells and MG-63 osteosarcoma cells showed excellent viability (similar to 98% and similar to 96%, respectively) and adhesion onto the HEMG coating after 96 h of incubation, indicating the integrity and biosafety of this surface. The cell viability and proliferation on the HEA and Ti (used as a benchmark) surfaces were much inferior. The enhanced surface protection and the superior biocompatibility makes the HEMG promising to be employed as a biocoating on orthopedic implants. (AU) | |
| Processo FAPESP: | 19/18460-4 - Desenvolvimento e propriedades termomecânicas e tribológicas de materiais multicomponentes avançados de alta entropia |
| Beneficiário: | Fernando Alvarez |
| Modalidade de apoio: | Auxílio à Pesquisa - Regular |
| Processo FAPESP: | 19/04943-3 - Ação de IGFBP7 sobre as vias TGFb/p53 e a resistência aos corticóides na Leucemia Linfoide Aguda |
| Beneficiário: | Leonardo Luís Artico |
| Modalidade de apoio: | Bolsas no Brasil - Doutorado |
| Processo FAPESP: | 18/24461-0 - Estudo e desenvolvimento de filmes finos de ligas de alta entropia (LAE-F) |
| Beneficiário: | Felipe Cemin |
| Modalidade de apoio: | Bolsas no Brasil - Pós-Doutorado |