| Texto completo | |
| Autor(es): |
Bernardes Spexoto, Maria Claudia
;
Ramirez, Paula Camila
;
Maximo, Roberta de Oliveira
;
Steptoe, Andrew
;
de Oliveira, Cesar
;
Alexandre, Tiago da Silva
Número total de Autores: 6
|
| Tipo de documento: | Artigo Científico |
| Fonte: | AGE AND AGEING; v. 51, n. 7, p. 10-pg., 2022-07-01. |
| Resumo | |
Objectives to analyse the accuracy of grip strength and gait speed in identifying mortality; to compare the association between mortality and sarcopenia defined by the EWGSOP1 and EWGSOP2 using the best cut-off found in the present study and those recommended in the literature and to test whether slowness is better than these two definitions to identify the risk of death in older adults. Methods a longitudinal study was conducted involving 6,182 individuals aged 60 or older who participated in the English Longitudinal Study of Ageing. Sarcopenia was defined based on the EWGSOP1 and EWGSOP2 using different cut-off for low muscle strength (LMS). Mortality was analysed in a 14-year follow-up. Results compared with the LMS definitions in the literature (<32, <30, <27 and < 26 kg for men; <21, <20 and < 16 kg for women), the cut-off of <36 kg for men (sensitivity = 58.59%, specificity = 72.96%, area under the curve [AUC] = 0.66) and < 23 kg for women (sensitivity = 68.90%, specificity = 59.03%, AUC = 0.64) as well as a low gait speed (LGS) <= 0.8 m/s (sensitivity = 53.72%, specificity = 74.02%, AUC = 0.64) demonstrated the best accuracy for mortality. Using the cut-off found in the present study, probable sarcopenia [HR = 1.30 (95%CI: 1.16-1.46)], sarcopenia [HR = 1.48 (95%CI: 1.24-1.78)] and severe sarcopenia [HR = 1.78 (95%CI: 1.49-2.12)] according to EWGSOP2 were better predictors of mortality risk than EWGSOP1. LGS <= 0.8 m/s was a better mortality risk predictor only when LMS was defined by low cut-off. Conclusions using LMS <36 kg for men and < 23 kg for women and LGS <= 0.8 m/s, EWGSOP2 was the best predictor for mortality risk in older adults. (AU) | |
| Processo FAPESP: | 18/13917-3 - Envelhecimento musculoesquelético: repercussões metabólicas, funcionais e risco de mortalidade em pessoas com mais de 50 anos de idade |
| Beneficiário: | Tiago da Silva Alexandre |
| Modalidade de apoio: | Auxílio à Pesquisa - Jovens Pesquisadores |