Viability of ex-vivo myography as a diagnostic tool for rectus abdominis muscle electrical activity collected at Cesarean section within a diamater cohort study

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Reyes, David R. A. ; Barbosa, Angelica M. P. ; Juliana, Floriano F. ; Sofia, Quiroz B. C., V ; Costa, Sarah M. B. ; Hallur, Raghavendra L. S. ; Enriquez, Eusebio M. A. ; Oliveira, Rafael G. ; Rossignolli, Patricia de Souza ; Pedroni, Cristiane Rodrigues ; Alves, Fernanda C. B. ; Garcia, Gabriela A. ; Abbade, Joelcio F. ; Carvalho, Carolina N. F. ; Sobrevia, Luis ; Rudge, Marilza V. C. ; Calderon, Iracema I. M. P. ; Diamater Study Grp

• Tipo de documento: Artigo Científico
• Fonte: BIOMEDICAL ENGINEERING ONLINE; v. 21, n. 1, p. 12-pg., 2022-10-14.

Resumo

Background Ex-vivo myography enables the assessment of muscle electrical activity response. This study explored the viability of determining the physiological responses in muscles without tendon, as rectus abdominis muscle (RAM), through ex-vivo myography to assess its potential as a diagnostic tool. Results All tested RAM samples (five different samples) show patterns of electrical activity. A positive response was observed in 100% of the programmed stimulation. RAM 3 showed greater weight (0.47 g), length (1.66 cm), and width (0.77 cm) compared to RAM 1, RAM 2, RAM 4 and RAM 5 with more sustained electrical activity over time, a higher percentage of fatigue was analyzed at half the time of the electrical activity. The order of electrical activity (Mn) was RAM 3 > RAM 5 > RAM 1 > RAM 4 > RAM 2. No electrical activity was recorded in the Sham group. Conclusions This study shows that it is feasible to assess the physiological responses of striated muscle without tendon as RAM, obtained at C-section, under ex vivo myography. These results could be recorded, properly analyzed, and demonstrated its potential as a diagnostic tool for rectus abdominis muscle electrical activity. (AU)

• Processo FAPESP: 16/01743-5 - Coorte da tríade gestacional: hiperglicemia, incontinência urinária e perfil clínico, molecular e ômico da miopatia hiperglicêmica na predição de incontinência e disfunção muscular e pesquisa translacional com biodevice para regeneração muscular em ratas
• Beneficiário: Marilza Vieira Cunha Rudge
• Modalidade de apoio: Auxílio à Pesquisa - Temático
• Processo FAPESP: 18/10661-8 - Coorte da tríade gestacional hiperglicemia, incontinência urinária e perfil clínico, molecular e ômico da miopatia hiperglicêmica na predição de incontinência e disfunção muscular e pesquisa translacional com biodevice para regeneração muscular em ratas.
• Beneficiário: David Rafael Abreu Reyes
• Modalidade de apoio: Bolsas no Brasil - Pós-Doutorado