Tissue response to different incision tools in animal model

Autor(es)

Torres-Augusto Neto, Renato ; Comachio, Cassio Amaro ; de Almeida, Lilian Caldas Quirino ; de Azambuja Carvalho, Pedro Henrique ; dos Santos Trento, Guilherme ; Pereira-Filho, Valfrido Antonio

• Tipo de documento: Artigo Científico
• Fonte: ORAL AND MAXILLOFACIAL SURGERY-HEIDELBERG; v. N/A, p. 8-pg., 2022-08-02.

Resumo

Purpose The aim of this study is to compare the repair of incisions performed with microdissection electrocautery tip, conventional electrocautery tip, high potency diode laser, and conventional scalpel blade in a in vivo model. Methods Different incisions were performed in adults Holtzman rats using the four types of instruments: microdissection electrocautery tip, conventional electrocautery tip, high potency diode laser, and conventional scalpel blade, in different periods of healing process. Thirty rats were divided into 5 groups, according to the period of euthanasia-24 h, 48 h, 72 h, 7 days, and 14 days. All animals received four incisions, each by a different method. Quantitative histological and histomorphometric analyses were performed using hematoxylin and eosin (HE) and Picrosirius Red staining. Results Inflammatory profile and tissue repair presented small statistically significance differences comparing conventional scalpel blade and microdissection tip; moreover, both presented quantitatively superior to the others. Conclusion It is believed that the microdissection tip can perform a dynamic incision just as a common scalpel blade, but more effective. Furthermore, it can promote a better hemostatic control of the surgical field that is comparable to conventional electrocautery tip without affecting tissue repair. (AU)

• Processo FAPESP: 17/19363-7 - Comparação do reparo tecidual após incisões com laser de diodo, bisturi elétrico e lâmina fria: avaliação histomorfométrica em ratos
• Beneficiário: Cássio Amaro Comachio
• Modalidade de apoio: Bolsas no Brasil - Iniciação Científica