Competitive Host-guest Electrochemical Detection of Ivermectin Drug Using a beta-cyclodextrin/Graphene-based Electrode

Autor(es)

Silva, Martin K. L. ; Simoes, Rafael P. ; Leao, Alcides L. ; Lapa, Rainer M. L. ; Rascon, Jesus ; Cesarino, Ivana

• Tipo de documento: Artigo Científico
• Fonte: Electroanalysis; v. N/A, p. 13-pg., 2022-05-31.

Resumo

The present study describes the novel development and application of an ivermectin (IVM) sensing electrochemical platform based on reduced graphene oxide (rGO) and the macrocyclic host beta-cyclodextrin (beta-CD) molecule. The sensing method was based in the host-guest characteristics of beta-CD and competitive interaction between the target analyte and the methylene blue (MB) redox probe. Differential pulse voltammetry (DPV) was employed for the detection of IVM and a linear response between 0.5 and 40.0 mu mol L-1 with a limit of detection of 0.25 mu mol L-1 was obtained using the glassy carbon (GC)/rGO/beta-CD electrode. The sensing platform was successfully applied for the detection of IVM in tap water samples, which may expand the applications of beta-CD towards the analysis of other chemical species. (AU)

• Processo FAPESP: 17/24274-3 - Desenvolvimento de biossensor de glicose como ferramenta analítica visando a otimização da produção de etanol de segunda geração a partir de resíduos do abacaxizeiro
• Beneficiário: Ivana Cesarino
• Modalidade de apoio: Auxílio à Pesquisa - Programa BIOEN - Regular