Performance of organoclay in adsorptive uptake of antihypertensive losartan potassium: A comparative batch study using micro-grain activated carbon

Autor(es)

de Andrade, J. R. ; da Silva, M. G. C. ; Gimenes, M. L. ; Vieira, M. G. A.

• Tipo de documento: Artigo Científico
• Fonte: JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING; v. 8, n. 3, p. 10-pg., 2020-06-01.

Resumo

The antihypertensive losartan potassium is an emerging pharmaceutical contaminant that has been traced in aquatic media; hence, up-to-date water treatment methods are urged. This paper is the first of its kind to examine losartan uptake by adsorption using an organophilic clay, Spectrogel. In comparison, a micro-grain activated carbon (mu GAC) was employed. Adsorption kinetics, isotherms and thermodynamics were examined and characterizations were performed. Pseudo-first order, pseudo-second order, external diffusion, surface diffusion and pore diffusion models were adjusted to kinetic data, and Langmuir, Freundlich and Dubinin-Radushkevich models were correlated to isotherms. Adsorption mechanisms were elucidated for surface features and surface chemistry. The latter was unraveled to have a crucial role on losartan removal by Spectrogel. The best adsorbent dosage was stablished as 6 g/L and initial solution pH (2.5-10) had no significant impact on the process. Spectrogel exhibited faster kinetics and superior maximum adsorption capacity (similar to 2200 min, 0.0820 mmol/g) than mu GAC (similar to 2600 min, 0.0441 mmol/g). Compared to water or ethanol eluents, methanol showed the highest efficiency as desorption agent (65%). The results indicate that Spectrogel organoclay is a potential non-traditional adsorbent for losartan remediation. (AU)

• Processo FAPESP: 16/05007-1 - Remoção de fármacos residuais em solução aquosa por adsorventes alternativos
• Beneficiário: Meuris Gurgel Carlos da Silva
• Modalidade de apoio: Auxílio à Pesquisa - Regular