Advances in the phytochemical screening and biological potential of propolis

Autor(es)

de Almeida-Junior, Silvio ; Ferraz, Matheus Vitor Ferreira ; de Oliveira, Alex Roberto ; Maniglia, Fabiola Pansani ; Bastos, Jairo Kenupp ; Furtado, Ricardo Andrade

• Tipo de documento: Artigo Científico
• Fonte: FUNDAMENTAL & CLINICAL PHARMACOLOGY; v. 37, n. 5, p. 14-pg., 2023-04-24.

Resumo

Propolis is a natural resinous product collected from different parts of plants by bees and mixed with their salivary secretions. The occurrence of more than 180 different chemotypes has flavonoids, phenolic acids, esters, and phenolic aldehydes, as well as balsamic resins, beeswax, pollen, and essential and aromatic oils, among others. Its biological potential documented throughout the world justifies the need, from time to time, to organize reviews on the subject, with the intention of gathering and informing about the update on propolis. In this review (CRD42020212971), phytochemical advances, in vitro, in vivo, and clinical biological assays of pharmacological interest are showcased. The focus of this work is to present propolis clinical safety assays, antitumor, analgesic, antioxidant, anti-inflammatory, and antimicrobial activities. This literature review highlights propolis' promising biological activity, as it also suggests that studies associating propolis with nanotechnology should be further explored for enhanced bioprocessing applications. (AU)

• Processo FAPESP: 17/04138-8 - Realização de estudos químicos, analíticos, biológicos, farmacológicos e tecnológicos para preenchimento das lacunas no desenvolvimento do setor de própolis brasileiro
• Beneficiário: Jairo Kenupp Bastos
• Modalidade de apoio: Auxílio à Pesquisa - Temático